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Publications

Clarifying the evidence on SARS-CoV-2 antigen rapid tests in public health responses to COVID-19 – The Lancet

Most people infected with SARS-CoV-2 are contagious for 4–8 days.7 Specimens are generally not found to contain culture-positive (potentially contagious) virus beyond day 9 after the onset of symptoms, with most transmission occurring before day 5. This timing fits with the observed patterns of virus transmission (usually 2 days before to 5 days after symptom onset), which led public health agencies to recommend a 10-day isolation period. The short window of transmissibility contrasts with a median 22–33 days of PCR positivity (longer with severe infections and somewhat shorter among asymptomatic individuals). This suggests that 50–75% of the time an individual is PCR positive, they are likely to be post-infectious.

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)00425-6/fulltext

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Publications

COVID-19 RNA Based Vaccines and the Risk of Prion Disease – Microbiol Infect Dis. 2021, Dr. J. Bart Classen

There is an old saying in medicine that “the cure may be worse than the disease.” The phrase can be applied to vaccines. In the current paper the concern is raised that the RNA based COVID vaccines have the potential to cause more disease than the epidemic of COVID-19. This paper focuses on a novel potential adverse event mechanism causing prion disease which could be even more common and debilitating than the viral infection the vaccine is designed to prevent. While this paper focuses on one potential adverse event there are multiple other potential fatal adverse events as discussed below.

https://scivisionpub.com/pdfs/covid19-rna-based-vaccines-and-the-risk-of-prion-disease-1503.pdf

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Opinion Videos

Ivor Cummins on The James Delingpole Channel

Ivor Cummins aka the Fat Emperor – gives James the lowdown on why you can’t trust anything our governments tell us about Covid-19. If you want the facts on Coronavirus – how deadly is it? do lockdowns and masks work? how does it compare with previous pandemics? – you’ve come to the right place

Please support the Delingpod:

Mirror archives are available below if this video is removed from YouTube.

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Opinion

As people test positive WEEKS after they stop being infectious, why I fear this mania for mass Covid testing is a hugely expensive blunder – Dr Tom Jefferson, Daily Mail

The PCR verdict cannot tell these individuals whether they need to self-isolate or whether they might need treatment – the things that really matter to them and society.

n some cases, for example, viral RNA might be present in such very low quantities that an individual is not at all infectious and poses zero danger. In other cases, the swabs might pick up RNA which is so old it is completely dead, as people continue shedding material from the virus up to 80 days after the initial infection.

I believe these people are testing positive time and time again.

https://web.archive.org/web/20201213092131/https://www.dailymail.co.uk/health/article-9046363/DR-TOM-JEFFERSON-fear-mania-mass-Covid-testing-hugely-expensive-blunder.html

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Publications

Informed consent disclosure to vaccine trial subjects of risk of COVID-19 vaccines worsening clinical disease – National Center for Biotechnology Information

COVID-19 vaccines designed to elicit neutralising antibodies may sensitise vaccine recipients to more severe disease than if they were not vaccinated. Vaccines for SARS, MERS and RSV have never been approved, and the data generated in the development and testing of these vaccines suggest a serious mechanistic concern: that vaccines designed empirically using the traditional approach (consisting of the unmodified or minimally modified coronavirus viral spike to elicit neutralising antibodies), be they composed of protein, viral vector, DNA or RNA and irrespective of delivery method, may worsen COVID-19 disease via antibody-dependent enhancement (ADE). This risk is sufficiently obscured in clinical trial protocols and consent forms for ongoing COVID-19 vaccine trials that adequate patient comprehension of this risk is unlikely to occur, obviating truly informed consent by subjects in these trials.

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Publications

No evidence for increased transmissibility from recurrent mutations in SARS-CoV-2 – Nature

COVID-19 is caused by the coronavirus SARS-CoV-2, which jumped into the human population in late 2019 from a currently uncharacterised animal reservoir. Due to this recent association with humans, SARS-CoV-2 may not yet be fully adapted to its human host. This has led to speculations that SARS-CoV-2 may be evolving towards higher transmissibility. The most plausible mutations under putative natural selection are those which have emerged repeatedly and independently (homoplasies). Here, we formally test whether any homoplasies observed in SARS-CoV-2 to date are significantly associated with increased viral transmission. To do so, we develop a phylogenetic index to quantify the relative number of descendants in sister clades with and without a specific allele. We apply this index to a curated set of recurrent mutations identified within a dataset of 46,723 SARS-CoV-2 genomes isolated from patients worldwide. We do not identify a single recurrent mutation in this set convincingly associated with increased viral transmission. Instead, recurrent mutations currently in circulation appear to be evolutionary neutral and primarily induced by the human immune system via RNA editing, rather than being signatures of adaptation. At this stage we find no evidence for significantly more transmissible lineages of SARS-CoV-2 due to recurrent mutations.

https://web.archive.org/web/20201125121534/https://www.nature.com/articles/s41467-020-19818-2

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Publications

No evidence for increased transmissibility from recurrent mutations in SARS-CoV-2 – Nature

We do not identify a single recurrent mutation in this set convincingly associated with increased viral transmission. Instead, recurrent mutations currently in circulation appear to be evolutionary neutral and primarily induced by the human immune system via RNA editing, rather than being signatures of adaptation. At this stage we find no evidence for significantly more transmissible lineages of SARS-CoV-2 due to recurrent mutations.

https://web.archive.org/web/20201125121534/https://www.nature.com/articles/s41467-020-19818-2

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Publications

Covid-19: the problems with case counting – BMJ

While the testing data are so opaque, using them to direct local lockdowns is unhelpful, argues Heneghan. “The testing is there to drive the test and trace strategy,” he says. “But what seems to be happening is that, as soon as we see an outbreak, there tends to be panic and over-reacting. This is a huge problem because politicians are operating in a non-evidence-based way when it comes to non-drug interventions.”

https://web.archive.org/web/20200904104824/https://www.bmj.com/content/370/bmj.m3374.full