Professor Sucharit Bhakdi, one of the first medical experts to speak out against the Covid hysteria, is being prosecuted in Germany. Please see the resources below for more information.
SARS-CoV-2
COVID-19 is a disease defined by symptoms and is not a virus. It’s therefore not transmitted nor can you test for it using nasal or throat testing kits. SARS-CoV-2 is the coronavirus that prompted the worldwide pandemic response.
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But whatever the reason, mask mandates were a fool’s errand from the start. They may have created a false sense of safety — and thus permission to resume semi-normal life. They did almost nothing to advance safety itself. The Cochrane report ought to be the final nail in this particular coffin.
There’s a final lesson. The last justification for masks is that, even if they proved to be ineffective, they seemed like a relatively low-cost, intuitively effective way of doing something against the virus in the early days of the pandemic. But “do something” is not science, and it shouldn’t have been public policy. And the people who had the courage to say as much deserved to be listened to, not treated with contempt. They may not ever get the apology they deserve, but vindication ought to be enough.
Jefferson and his colleagues also looked at the evidence for social distancing, hand washing, and sanitising/sterilising surfaces — in total, 78 randomised trials with over 610,000 participants.
Jefferson doesn’t grant many interviews with journalists — he doesn’t trust the media. But since we worked together at Cochrane a few years ago, he decided to let his guard down with me.
Interestingly, 12 trials in the review, ten in the community and two among healthcare workers, found that wearing masks in the community probably makes little or no difference to influenza-like or Covid-19-like illness transmission. Equally, the review found that masks had no effect on laboratory-confirmed influenza or SARS-CoV-2 outcomes. Five other trials showed no difference between one type of mask over another.
https://archive.today/2023.02.03-091622/https://www.spectator.co.uk/article/do-mask-mandates-work/
There is uncertainty about the effects of face masks. The low to moderate certainty of evidence means our confidence in the effect estimate is limited, and that the true effect may be different from the observed estimate of the effect. The pooled results of RCTs did not show a clear reduction in respiratory viral infection with the use of medical/surgical masks. There were no clear differences between the use of medical/surgical masks compared with N95/P2 respirators in healthcare workers when used in routine care to reduce respiratory viral infection. Hand hygiene is likely to modestly reduce the burden of respiratory illness, and although this effect was also present when ILI and laboratory‐confirmed influenza were analysed separately, it was not found to be a significant difference for the latter two outcomes. Harms associated with physical interventions were under‐investigated.
Results
A total of 2840 participants completed the survey between December 18 and 23, 2021. 51% (1383 of 2840) of the participants were female and the mean age was 47 (95% CI 46.36–47.64) years. Those who knew someone who experienced a health problem from COVID-19 were more likely to be vaccinated (OR: 1.309, 95% CI 1.094–1.566), while those who knew someone who experienced a health problem following vaccination were less likely to be vaccinated (OR: 0.567, 95% CI 0.461–0.698). 34% (959 of 2840) reported that they knew at least one person who had experienced a significant health problem due to the COVID-19 illness. Similarly, 22% (612 of 2840) of respondents indicated that they knew at least one person who had experienced a severe health problem following COVID-19 vaccination. With these survey data, the total number of fatalities due to COVID-19 inoculation may be as high as 278,000 (95% CI 217,330–332,608) when fatalities that may have occurred regardless of inoculation are removed.Conclusion
Knowing someone who reported serious health issues either from COVID-19 or from COVID-19 vaccination are important factors for the decision to get vaccinated. The large difference in the possible number of fatalities due to COVID-19 vaccination that emerges from this survey and the available governmental data should be further investigated.
Academic freedom at Stanford is clearly dying. It cannot survive if the administration fails to create an environment where good-faith discussions can occur outside of a framework of ideological rigidity and the false certainties that ideologues—and governments—wish to impose on us. Stanford missed the opportunity to sponsor COVID policy forums and it deplatformed dissenting voices. Several prominent faculty exploited this environment, engaging in actions that directly violated basic academic norms.
RNA vaccines are efficient preventive measures to combat the SARS-CoV-2 pandemic. High levels of neutralizing SARS-CoV-2-antibodies are an important component of vaccine-induced immunity. Shortly after the initial two mRNA vaccine doses, the IgG response mainly consists of the pro-inflammatory subclasses IgG1 and IgG3. Here, we report that several months after the second vaccination, SARS-CoV-2-specific antibodies were increasingly composed of non-inflammatory IgG4, which were further boosted by a third mRNA vaccination and/or SARS-CoV-2 variant breakthrough infections. IgG4 antibodies among all spike-specific IgG antibodies rose on average from 0.04% shortly after the second vaccination to 19.27% late after the third vaccination. This induction of IgG4 antibodies was not observed after homologous or heterologous SARS-CoV-2 vaccination with adenoviral vectors. Single-cell sequencing and flow cytometry revealed substantial frequencies of IgG4-switched B cells within the spike-binding memory B-cell population (median 14.4%; interquartile range (IQR) 6.7–18.1%) compared to the overall memory B-cell repertoire (median 1.3%; IQR 0.9–2.2%) after three immunizations. Importantly, this class switch was associated with a reduced capacity of the spike-specific antibodies to mediate antibody-dependent cellular phagocytosis and complement deposition. Since Fc-mediated effector functions are critical for antiviral immunity, these findings may have consequences for the choice and timing of vaccination regimens using mRNA vaccines, including future booster immunizations against SARS-CoV-2.
http://archive.today/2023.01.02-215315/https://www.science.org/doi/10.1126/sciimmunol.ade2798
The bivalent COVID-19 vaccine given to working-aged adults afforded modest protection overall against COVID-19, while the virus strains dominant in the community were those represented in the vaccine.
http://archive.today/2022.12.21-161132/https://www.medrxiv.org/content/10.1101/2022.12.17.22283625v1
In March 2020, some colleagues in Parliament, knowing I was interested in genetics and medicine, asked me if I thought Covid began with a lab leak. “No,” I replied confidently. In this I relied on conversations with expert virologists and a paper that five of them published in Nature Medicine categorically ruling it out: “Our analyses clearly show that Sars-CoV-2 is not a laboratory construct or a purposely manipulated virus.”
Today, I feel betrayed. Thanks to emails released under Freedom of Information this week, we now know that they did think a lab leak was possible, and the evidence that they then used to dismiss it was faulty.
Conclusion
SARS-CoV-2 vaccination was associated with higher risk of myocarditis death, not only in young adults but also in all age groups including the elderly. Considering healthy vaccinee effect, the risk may be 4 times or higher than the apparent risk of myocarditis death. Underreporting should also be considered. Based on this study, risk of myocarditis following SARS-CoV-2 vaccination may be more serious than that reported previously.
https://www.medrxiv.org/content/10.1101/2022.10.13.22281036v1
“SARS-CoV-2 is not causing mass illness and death.”
On today’s show Mike Yeadon chats about the COVID era and his journey, including whether or not SARS exists. He has evolved a bunch of his views.GUEST OVERVIEW: Mike Yeadon was chief scientist and vice-president of the allergy and respiratory research division of Pfizer.
https://tntradiolive.podbean.com/e/mike-yeadon-on-jerm-warfare-with-jeremy-nell-03-october-2022/
Results
Pfizer and Moderna mRNA COVID-19 vaccines were associated with an excess risk of serious adverse events of special interest of 10.1 and 15.1 per 10,000 vaccinated over placebo baselines of 17.6 and 42.2 (95 % CI −0.4 to 20.6 and −3.6 to 33.8), respectively. Combined, the mRNA vaccines were associated with an excess risk of serious adverse events of special interest of 12.5 per 10,000 vaccinated (95 % CI 2.1 to 22.9); risk ratio 1.43 (95 % CI 1.07 to 1.92). The Pfizer trial exhibited a 36 % higher risk of serious adverse events in the vaccine group; risk difference 18.0 per 10,000 vaccinated (95 % CI 1.2 to 34.9); risk ratio 1.36 (95 % CI 1.02 to 1.83). The Moderna trial exhibited a 6 % higher risk of serious adverse events in the vaccine group: risk difference 7.1 per 10,000 (95 % CI –23.2 to 37.4); risk ratio 1.06 (95 % CI 0.84 to 1.33). Combined, there was a 16 % higher risk of serious adverse events in mRNA vaccine recipients: risk difference 13.2 (95 % CI −3.2 to 29.6); risk ratio 1.16 (95 % CI 0.97 to 1.39).
Discussion
The excess risk of serious adverse events found in our study points to the need for formal harm-benefit analyses, particularly those that are stratified according to risk of serious COVID-19 outcomes. These analyses will require public release of participant level datasets.
The risk of myocarditis in this large cohort study was highest in young males after the second SARS-CoV-2 vaccine dose, and this risk should be balanced against the benefits of protecting against severe COVID-19 disease.
https://jamanetwork.com/journals/jamacardiology/fullarticle/2791253
Archive link: https://web.archive.org/web/20230000000000*/https://jamanetwork.com/journals/jamacardiology/fullarticle/2791253
Genetic match discovered in Covid’s unique furin cleavage site on spike protein
Matched genetic sequence patented by Moderna for cancer research purposes
Researchers say one in 3trillion chance Covid developed the code naturally
RESULTS Of 1050 eligible HCW, 154 and 120 were enrolled to receive BNT162b2 and mRNA1273, respectively, and compared to 426 age-matched controls. Recipients of both vaccine types had a ∼9-10-fold increase in IgG and neutralizing titers within 2 weeks of vaccination and an 8-fold increase in live Omicron VOC neutralization, restoring titers to those measured after the third vaccine dose. Breakthrough infections were common, mostly very mild, yet, with high viral loads. Vaccine efficacy against infection was 30% (95%CI:-9% to 55%) and 11% (95%CI:-43% to +43%) for BNT162b2 and mRNA1273, respectively. Local and systemic adverse reactions were reported in 80% and 40%, respectively.
CONCLUSIONS The fourth COVID-19 mRNA dose restores antibody titers to peak post-third dose titers. Low efficacy in preventing mild or asymptomatic Omicron infections and the infectious potential of breakthrough cases raise the urgency of next generation vaccine development.
https://www.medrxiv.org/content/10.1101/2022.02.15.22270948v1.full-text
One of the checks and balances on rampant bad scientific research is to continuously assess how new ideas fit into the framework of the bigger picture. A new piece of information may seem perfectly reasonable and well-documented, but the domino effect of its implications gives you another way to test its validity. When multiple lines of seemingly rock-solid evidence contradict one another, that’s a good sign that something is wrong, even if you don’t yet know why. Whenever a thread seems out of place, it’s time to pull on that thread until you can figure out what exactly is going on.
…”Trusting the science” is not (and never has been) about trusting results or trusting experts. Trusting the scientists is what got us into this mess. For science to function properly, we must NOT trust the scientists. Instead, we must trust in the messy self-correcting process that allows truth to boil to the surface even if every participant in that process is flawed.
“Science is the belief in the ignorance of the Experts”
— Richard P. FeynmanScience is the relentless competition between measurable pieces of evidence, the ruthless gauntlet of debate, the willingness to question even the most “obvious” of assumptions, and the humbleness to test and retest any and all assumptions against hard evidence, most especially when those assumptions are our own.
https://www.juliusruechel.com/2022/01/who-do-you-trust-if-you-cant-trust.html
Cross-reactive immune responses to SARS-CoV-2 have been observed in pre-pandemic cohorts and proposed to contribute to host protection. Here we assess 52 COVID-19 household contacts to capture immune responses at the earliest timepoints after SARS-CoV-2 exposure. Using a dual cytokine FLISpot assay on peripheral blood mononuclear cells, we enumerate the frequency of T cells specific for spike, nucleocapsid, membrane, envelope and ORF1 SARS-CoV-2 epitopes that cross-react with human endemic coronaviruses. We observe higher frequencies of cross-reactive (p = 0.0139), and nucleocapsid-specific (p = 0.0355) IL-2-secreting memory T cells in contacts who remained PCR-negative despite exposure (n = 26), when compared with those who convert to PCR-positive (n = 26); no significant difference in the frequency of responses to spike is observed, hinting at a limited protective function of spike-cross-reactive T cells. Our results are thus consistent with pre-existing non-spike cross-reactive memory T cells protecting SARS-CoV-2-naïve contacts from infection, thereby supporting the inclusion of non-spike antigens in second-generation vaccines.
http://archive.today/2022.01.10-120437/https://www.nature.com/articles/s41467-021-27674-x
People with high levels of T cells from common colds are less likely to catch COVID, according to a new peer-reviewed study.
Researchers said the findings could help provide the blueprint for the production of new vaccines which give longer-lasting immunity and would protect against current and future coronavirus variants such as Omicron and Delta.
Archive of study: https://evidencenotfear.com/cross-reactive-memory-t-cells-associate-with-protection-against-sars-cov-2-infection-in-covid-19-contacts-nature-communications/
These data suggest that virtually all individuals with existing anti-SARS-CoV-2 CD8+ T-cell responses should recognize the Omicron VOC, and that SARS-CoV-2 has not evolved extensive T-cell escape mutations at this time.
http://archive.today/2021.12.12-062920/https://www.biorxiv.org/content/10.1101/2021.12.06.471446v1