Categories
Publications

SARS-CoV-2 elicits robust adaptive immune responses regardless of disease severity – Science Direct

We report broad serological profiles within the cohort, detecting antibody binding to other human coronaviruses. 202(>99%) participants had SARS-CoV-2 specific antibodies, with SARS-CoV-2 neutralization and spike-ACE2 receptor interaction blocking observed in 193(95%) individuals. A significant positive correlation (r=0.7804) between spike-ACE2 blocking antibody titers and neutralization potency was observed. Further, SARS-CoV-2 specific CD8+ T-cell responses were clear and quantifiable in 95 of 106(90%) HLA-A2+ individuals.

https://www.sciencedirect.com/science/article/pii/S2352396421002036

Categories
Opinion

As a GP in the NHS I witnessed first-hand the catastrophic way Matt Hancock failed the old and vulnerable in care homes – Dr Malcolm Kendrick, RT

The Health Secretary claims he “tried” to throw a protective ring around care homes but, from my experience in the early days of the pandemic, he couldn’t have come up with a more disastrous and deadly policy.

As a GP working mainly with elderly patients in care homes and intermediate care I witnessed, at first hand, the absolute disaster that was the government policy at the start of the Covid-19 outbreak. Elderly patients who were Covid-19 positive, or not tested, or perhaps even negative, were simply shovelled out of hospitals and into care homes. ‘The hospitals must be cleared out… nothing else matters.

https://www.rt.com/op-ed/526539-catastrophic-care-homes-matt-hancock/

Categories
Videos

Dr. Peter McCullough interview by John Leake

Dr. Peter McCullough has been the world’s most prominent and vocal advocate for early outpatient treatment of SARS-CoV-2 (COVID-19) infection in order to prevent hospitalization and death. On May 19, 2021, I interviewed him about his efforts as a treating physician and researcher. From his unique vantage point, he has observed and documented a profoundly disturbing policy response to the pandemic—a policy response that may prove to be the greatest malpractice and malfeasance in the history of medicine and public health.”

Link to interview audio format released by Julian Charles of The Mind Renewed podcast.

Backup mirror:

Categories
Videos

Dr. Roger Hodkinson – Investigative Corona Committee Germany Session 56

Dr Hodkinson is the CEO of Western Medical Assessments, and has been the Company’s Medical Director for over 20 years. He received his general medical degrees from Cambridge University in the UK, and then became a Royal College certified pathologist in Canada (FRCPC) following a residency in Vancouver, BC.

Source: Western Medical Assessments
  • Dr Hodkinson’s interview is at 2h49m.

Find out more about the Investigative Corona Committee Germany.

The video at https://youtu.be/OjhM3XRN5js?t=10145 has been removed from YouTube

Backup mirrors:

A shortened version of the video Session 56 has been uploaded to Bitchute by Coronavirus Plushie.

Categories
Videos

Investigative Corona Committee Germany Session 56 (Full video)

Dr. Michael Dykta, Dr. Wolfgang Wodarg, Professor Arne Burkhardt, Dr. Peter McCullough and Dr. Roger Hodkinson speak with Dr. Reiner Fuellmich on Germany’s Investigative Corona Committee Session 56.

  • Dr McCullough’s is at around 1h35m.
  • Dr Hodkinson’s interview is at 2h49m.

Find out more about the Investigative Corona Committee Germany.

The full video has been removed from YouTube. You can find a backup mirror below:

Categories
Opinion Videos

Covid is the cure worse than the disease? Dr John Lee, Unlocked

Unlocked Exclusive — in a hard-hitting interview, retired NHS pathologist Dr John Lee discusses the government’s response to the pandemic, analyses why proven scientific procedures were abandoned, makes the case for ending Lockdown now, and asks the question most doctors are unable to discuss in public. Covid-19: is the cure worse than the disease?

Backup mirrors:

https://www.facebook.com/unlockedunitedkingdom/videos/506787697359395/

Categories
News

How busy are hospitals in England? – BBC News

When announcing the national lockdown, Prime Minister Boris Johnson said the NHS risked being overwhelmed if the measures weren’t taken.

But statistics suggest that the proportion of beds currently occupied by patients is actually lower than usual.

So how can both things be true?

…To create that wiggle room, there has been a big decrease in patients coming in for non-urgent operations and outpatient appointments, to ensure that space is there and pressures are not increased.

Even in September 2020, when hospitals were beginning to increase the number of operations carried out, these were still 25% lower than in previous years.

This also helps explain why there are also fewer patients in hospitals this year, as well as fewer beds.

The impact of this is a large backlog and the potential for certain treatments – such as cancer care – being delayed.

https://web.archive.org/web/20210107152338/https://www.bbc.co.uk/news/55536762

Categories
Opinion

Why did the world react so hysterically to covid? – Sebastian Rushworth M.D.

  • The mortality rate is below 0.2%.
  • For most people the risk of dying if you get infected is less than one in 500 (and less than one in 3,000 if you’re below 70 years of age).
  • The disease preferentially strikes people who are anyway very close to the end of life/
  • The amount of lifetime lost when someone dies of the disease is usually small.
  • 2020 will likely turn out to have been a very average year in terms of overall mortality.
  • 98% of people who get covid are fully recovered within three months.
  • There is no good evidence that covid results in long term health consequences.
  • Chinese realized early on that covid-19 wasn’t very serious, no worse than a bad flu.
  • China is still reporting less than 20 cases per day.
  • China is claiming that less than 5,000 people have so far died of covid in China. That’s less than Sweden, a country with less than 1% of China’s population.
Categories
News

Hospitals Retreat From Early Covid Treatment and Return to Basics – WSJ

Around one-third of hospital deaths during the initial COVID-19 peak were due to inappropriate treatment.

“We were intubating sick patients very early. Not for the patients’ benefit, but in order to control the epidemic & to save other patients,” Dr. Iwashyna said “That felt awful.”

…As a safety precaution, doctors and hospitals limited the access of health-care workers to coronavirus patients on ventilators, giving them fewer opportunities to check on them. That meant patients required more powerful sedatives to keep them from pulling out throat tubes.

…Overall, survival for Covid-19 patients increased 28% from April to September at HCA hospitals.

…Before the pandemic, between about 30% to more than 40% of ventilator patients died, according to research. Numbers were sharply higher in Wuhan, China. As the pandemic grew, hospitals in the U.S. reported death rates in some cases of about 50% for ventilated Covid-19 patients.

https://web.archive.org/web/20201220193305/https://www.wsj.com/articles/hospitals-retreat-from-early-covid-treatment-and-return-to-basics-11608491436

Categories
Publications

Effects of non-pharmaceutical interventions on COVID-19: A Tale of Three Models – medRxiv

Results While model 1 found that lockdown was the most effective measure in the original 11 countries, model 2 showed that lockdown had little or no benefit as it was typically introduced at a point when the time-varying reproductive number was already very low. Model 3 found that the simple banning of public events was beneficial, while lockdown had no consistent impact. Based on Bayesian metrics, model 2 was better supported by the data than either model 1 or model 3 for both time horizons.

Conclusions Inferences on effects of NPIs are non-robust and highly sensitive to model specification. Claimed benefits of lockdown appear grossly exaggerated.

https://www.medrxiv.org/content/10.1101/2020.07.22.20160341v3

Categories
Publications

Covid-19: The lost lessons of Tamiflu – BMJ

While the truth about Tamiflu emerged only after years of exhaustive work by the Cochrane review group and investigative journalists, the machinations behind remdesivir’s rapid climb were evident at an early stage. On 29 April, the same day as a trial was published showing no significant effect of remdesivir among patients in hospital, remdesivir’s manufacturer rushed out interim findings of a more favourable trial by press release and with full White House honours. The much vaunted but minimal benefits shown in severely ill people were used to justify FDA approvals and worldwide purchase. Now a much larger trial has found little or no benefit in hospital patients, and a BMJ Rapid Recommendation, produced in collaboration with the World Health Organization and Magic App, has come down against use of remdesivir in patients with covid-19 of any severity.

…Science by press release, on the basis of interim or ad hoc analyses, and without access to the data, also afflicts our knowledge about the covid-19 candidate vaccines. Patients and the public deserve better than this. So do health professionals. Pandemic or no pandemic, decisions must be based on scrutiny of the full data from trials that are independent of drug and vaccine manufacturers.

https://web.archive.org/web/20201205164516/https://www.bmj.com/content/371/bmj.m4701

Categories
Publications

UK Economic and fiscal outlook – UK Office for Budget Responsibility

The coronavirus pandemic has delivered the largest peacetime shock to the global economy on record. It has required the imposition of severe restrictions on economic and social life; driven unprecedented falls in national income; fuelled rises in public deficits and debt surpassed only in wartime; and created considerable uncertainty about the future.

…GDP is set to fall by 11 per cent this year – the largest drop in annual output since the Great Frost of 1709.

https://obr.uk/docs/ExecSumm_November_2020.pdf

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Publications

Predictive performance of international COVID-19 mortality forecasting models – medRxiv

The Imperial model had larger errors, about 5-fold higher than other models by six weeks. This appears to be largely driven by the aforementioned tendency to overestimate mortality. At twelve weeks, MAPE values were lowest for the IHME-MS-SEIR (23.7%) model, while the Imperial model had the most elevated MAPE (98.8%). Predictive performance between models was generally similar for median absolute errors (MAEs) 

https://www.medrxiv.org/content/10.1101/2020.07.13.20151233v5.full

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Publications

Covid-19 Mortality: A Matter of Vulnerability Among Nations Facing Limited Margins of Adaptation – Frontiers in Public Health

Results: Higher Covid death rates are observed in the [25/65°] latitude and in the [−35/−125°] longitude ranges. The national criteria most associated with death rate are life expectancy and its slowdown, public health context (metabolic and non-communicable diseases (NCD) burden vs. infectious diseases prevalence), economy (growth national product, financial support), and environment (temperature, ultra-violet index). Stringency of the measures settled to fight pandemia, including lockdown, did not appear to be linked with death rate.

Conclusion: Countries that already experienced a stagnation or regression of life expectancy, with high income and NCD rates, had the highest price to pay. This burden was not alleviated by more stringent public decisions. Inherent factors have predetermined the Covid-19 mortality: understanding them may improve prevention strategies by increasing population resilience through better physical fitness and immunity.

https://www.frontiersin.org/articles/10.3389/fpubh.2020.604339/full

Categories
Opinion

Have we got it all wrong when it comes to Covid? – The Irish Examiner

There is a case to be made that we as a country have been led by a conversation about the virus which has been unbalanced and disproportionate, writes Daniel McConnell

https://www.irishexaminer.com/opinion/columnists/arid-40081700.html

Categories
Opinion Publications

Covid-19: politicisation, “corruption,” and suppression of science – BMJ

Politicians and governments are suppressing science. They do so in the public interest, they say, to accelerate availability of diagnostics and treatments. They do so to support innovation, to bring products to market at unprecedented speed. Both of these reasons are partly plausible; the greatest deceptions are founded in a grain of truth. But the underlying behaviour is troubling.

Politicians and governments are suppressing science. They do so in the public interest, they say, to accelerate availability of diagnostics and treatments. They do so to support innovation, to bring products to market at unprecedented speed. Both of these reasons are partly plausible; the greatest deceptions are founded in a grain of truth. But the underlying behaviour is troubling.

Politicians and governments are suppressing science. They do so in the public interest, they say, to accelerate availability of diagnostics and treatments. They do so to support innovation, to bring products to market at unprecedented speed. Both of these reasons are partly plausible; the greatest deceptions are founded in a grain of truth. But the underlying behaviour is troubling.

The UK’s pandemic response provides at least four examples of suppression of science or scientists. First, the membership, research, and deliberations of the Scientific Advisory Group for Emergencies (SAGE) were initially secret until a press leak forced transparency.2 The leak revealed inappropriate involvement of government advisers in SAGE, while exposing under-representation from public health, clinical care, women, and ethnic minorities. Indeed, the government was also recently ordered to release a 2016 report on deficiencies in pandemic preparedness, Operation Cygnus, following a verdict from the Information Commissioner’s Office.

https://www.bmj.com/content/371/bmj.m4425

Categories
Opinion Publications

When good science is suppressed by the medical-political complex, people die – BMJ

The UK’s pandemic response relies too heavily on scientists and other government appointees with worrying competing interests, including shareholdings in companies that manufacture covid-19 diagnostic tests, treatments, and vaccines. Government appointees are able to ignore or cherry pick science—another form of misuse—and indulge in anti-competitive practices that favour their own products and those of friends and associates.

https://www.bmj.com/content/371/bmj.m4425

Categories
News

Government urged to focus on surge in unexplained non-Covid deaths at home – The Telegraph

Experts fear people still unable to access medical care even though there are now relatively few coronavirus cases in hospitals

Twice as many people are now dying at home from unexplained causes rather than Covid-19, with experts calling for an urgent investigation into what is causing the excess deaths.

The ONS figures show that deaths in hospitals continue to be much lower than usual, suggesting that many of the home deaths are people who would ordinarily have received hospital care.

https://www.telegraph.co.uk/news/2020/07/28/deaths-home-causes-coronavirus-increase-ons-figures-reveal/

Categories
Videos

Oxford epidemiologists: suppression strategy is not viable – UnHerd

2:55 – Masks
• Tom Jefferson: “Aside from people who are exposed on the frontlines, there is no evidence that masks make any difference, but what’s even more extraordinary is the uncertainty: we don’t know if these things make any difference…. We should have done randomised control trials in February, March and April but not anymore because viral circulation is low and we will need huge number of enrolees to show whether there was any difference”.
• Carl Heneghan: “By all means people can wear masks but they can’t say it’s an evidence-based decision… there is a real separation between an evidence-based decision and the opaque term that ‘we are being led by the science’, which isn’t the evidence”.

9:26 – Pandemic life cycle
• CH: “One of the keys of the infection is to look at who’s been infected, which shows a crucial difference when comparing the pandemic theory to seasonal theory. In a pandemic you’d expect to see young people disproportionately affected, but in the UK we’ve only had six child deaths, which is far less than we’d normally see in a pandemic. The high number of deaths with over-75s fits with the seasonal theory”.

14:00 – Covid seasonality
• CH: “The stability of the virus is far less when the temperature goes up but humidity seems to be particularly important. The lower the humidity, the more stable the virus is in the atmosphere and on surfaces… It’s now winter in the southern hemisphere, which is why places like Australia are suddenly having outbreaks.”

20:37 – Lockdown
• CH: “Many people said that we should have locked down earlier, but 50% of care homes developed outbreaks during the lockdown period so there are issues within the transmission of this virus that are not clear… Lockdown is a blunt tool and there needs to be intelligent conversations about what mitigation strategies can keep society functioning while we keep the most vulnerable shielded”.

25:20 – Nightingale hospitals
• CH: “They are the wrong structure. What you need is fever hospitals which were here until around the 1980s or 90s. They were on single floors and had isolation within isolation. Theere were no lift shafts and staff were trained, which meant that everyone was protected from each other… It looks like at leats 20% of people got the infection while they were in hospital”

27:30 – Suppression strategy
• CH: “The benefits of the current strategy are outweighed by the harms…When it comes to suppression, only the virus will have a determination in that. If you follow the New Zealand policy of suppressing it to zero and locking down the country forever, then you’re going to have a problem… This virus is so out there now, I cannot see a strategy that makes suppression the viable option. The strategy right now should be how we learn to live with this virus”

32:45 – Response to the virus
• TJ: “I am a survivor of four pandemics and for the other three, I didn’t even realise they were going on. People died but nothing changed and none of the fabric of society was eroded like this response… Do I see steps being taken at a European level about learning from our mistakes and changing policies? The answer is no…

39:30 – Politics of the virus
• CH: “We as individuals are part of the problem because sensationalism drives people to click and read the information. So it’s a big circle because we’ve created the problem — if we put the worst case scenario out there, we will go and have a look. If you want a solution, you’ve got to get people to stop clicking on this sensationalist stuff”.

43:30 – IFR
• CH: “We will be down about where we were with the swine flu: around 0.1-0.3% which is much lower than what we think because at the moment we are seeing the case fatality”.
• TJ: “If you look at the whole narrative, it was distorted from the very beginning by the obsession with influenza which was just one or two agents and nothing else existed. We’re no different now”.

Categories
News

How Many More Will Die From Fear of the Coronavirus? – New York Times

Cleveland Clinic CEO and Mayo Clinic President say the response to COVID-19 could be as big a disaster as the virus itself.

“The true cost of this epidemic will not be measured in dollars; it will be measured in human lives and human suffering. In the case of cancer alone, our calculations show we can expect a quarter of a million additional preventable deaths annually if normal care does not resume,” they wrote.

https://www.nytimes.com/2020/06/09/opinion/coronavirus-hospitals-deaths.html