Categories
Opinion

We’ll Have Herd Immunity by April – Wall Street Journal

Amid the dire Covid warnings, one crucial fact has been largely ignored: Cases are down 77% over the past six weeks. If a medication slashed cases by 77%, we’d call it a miracle pill. Why is the number of cases plummeting much faster than experts predicted?

In large part because natural immunity from prior infection is far more common than can be measured by testing. Testing has been capturing only from 10% to 25% of infections, depending on when during the pandemic someone got the virus. Applying a time-weighted case capture average of 1 in 6.5 to the cumulative 28 million confirmed cases would mean about 55% of Americans have natural immunity.

…explained only by natural immunity. Behavior didn’t suddenly improve over the holidays; Americans traveled more over Christmas than they had since March. Vaccines also don’t explain the steep decline in January. Vaccination rates were low and they take weeks to kick in.

https://www.wsj.com/articles/well-have-herd-immunity-by-april-11613669731

Categories
Publications

How kids’ immune systems can evade COVID – Nature

Young children account for only a small percentage of COVID-19 infections — a trend that has puzzled scientists. Now, a growing body of evidence suggests why: kids’ immune systems seem better equipped to eliminate SARS-CoV-2 than are adults’.

“Children are very much adapted to respond — and very well equipped to respond — to new viruses,” says Donna Farber, an immunologist at Columbia University in New York City. Even when they are infected with SARS-CoV-2, children are most likely to experience mild or asymptomatic illness.

Another clue that children’s response to the virus differs from that of adults is that some children develop COVID-19 symptoms and antibodies specific to SARS-CoV-2 but never test positive for the virus on a standard RT-PCR test. In one study, three children under ten from the same family developed SARS-CoV-2 antibodies — and two of them even experienced mild symptoms — but none tested positive on RT-PCR, despite being tested 11 times over 28 days while in close contact with their parents, who had tested positive.

https://web.archive.org/web/20201211205033/https://www.nature.com/articles/d41586-020-03496-7

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News

Quarter of people may already be immune to coronavirus – even though many have never been infected – The Telegraph

PHE researchers believe people with high levels of T-cells likely to have picked up immunity from coronaviruses like common cold

A quarter of people may already be immune to coronavirus even though many of them have never been infected, a new study by Public Health England (PHE) suggests.

https://www.telegraph.co.uk/news/2020/11/19/many-could-immune-covid-despite-never-having-infected-study/

Categories
Opinion Videos

Dr. Mike Yeadon on The James Delingpole Channel

Interview highlights

  • COVID-19 is not a dread disease that will kill everyone.
  • The initially high case fatality rate of COVID-19 was because the medical community didn’t know how to treat it.
  • The fatality rate of flu is 0.1% (1 in every 1,000 who are infected end up dying).
  • Ventilators are the wrong option if you do not have an obstructed airway disease.
  • Prod. Ioannidis: The infection fatality ratio of COVID-19 is 0.15%. This is pretty much the same as the flu.
  • We should just ask people to be careful but otherwise go about your daily life.
  • These things pass every year. This is the first ‘social media pandemic.’
  • The normal practice for intensive care beds in the NHS is to run them almost full. This is because a lot of intensive care bed assignment is planned.
  • ICU use at the height of the pandemic was has very low because the NHS was run as light as possible to cope with a second wave.
  • Respiratory viruses don’t do waves.
  • This is not opinion but is basic understanding among experts in the field. It is supposrted by the highest quality science. Sir Patrick Vallance knows this.
  • COVID-19 follows the Gompertz Curve.
  • You have immunity after your body has fought off a respiratory virus. If that was not the case, you’d be dead. Immunity probably lasts decades based on evidence from other viruses.
  • Gompertz Curve is identical in all heavily infection regions.
  • Something awefull happened in the middle of the year: PCR swab test.
  • It is not true that if you test more people you’ll save more lives. A certain percentage of the test will come up positive even if there’s no virus in you.
  • False positive rate wasn’t released.
  • Kate Barker wrote in a government document on June 3rd, 2020, to SAGE: test has an unknown false positive rate; based on similar tests it may be between 1%-2%. This is a big deal.
  • Based on 1%: for every 1,000 people you test, 10 will come back positive, even if they don’t have the virus. If prevalence is only 0.1% as reported by ONS, only 1 in 1,000 will be genuine. This means 9 in 10–in other words 90%–are false.
  • Pillar 2 testing would have caused of the most of the positives to be false.
  • 1,700 people die normally every day in the UK. During the summer, only about 10 were dying per day of covid.
  • More testing, more false positives. We’ll never escape covid if we keep testing because most of the positives will be false. This is immunology 101. Sir Patrick Vallance would have known this.
  • Influenza is a high mutation-rate virus. Coronaviruses are relatively stable so once you’ve recovered, you are probably immune for decades.
  • COVID-19 kills 0.15%-0.2%, slightly more lethal than the average flu. Once it’s gone through the population, it won’t come back.
  • 99.94% survive COVID-19 and will be resistant for a long time.
  • COVID-19 is 80% similar to SARS-COV-1.
  • People who were exposed to SARS have T-cell immunity 17 years later. Evidence for COVID-19 all point in direction.
  • Our bodies have many lines of defense, including innate immunity and T-cells. Antibodies are in the last line of defense.
  • Study shows around 30% prior immunity to SARS-COV-2. It was due to exposure to common-cold coronaviruses.
  • The claim made by Sir Patrick Vallance that more than 90% are susceptible is a lie.
  • Mass testing of the well populating is the worst problem as it generates false positives, fear and control.
  • If you’re immune, you can’t be infected or infectious. Herd immunity is already in play in London.
  • If SAGE is correct, London should be ‘ablaze’ with deaths.
  • Current testing methods are not forensically sound.
  • Tests detect common cold and dead virus.
  • SARS-COV-2 has never really been a public health emergency.
  • We do not need the vaccine to return to normal. Most people are not in danger from COVID-19. More people are in danger from car crashes and we accept that risk.
  • Best case scenario is that the vaccine is 50% effective. Natural immunity might be better.
  • The most vulnerable often don’t respond well to vaccines and die anyway.
  • SAGE is giving lethally wrong advice.
  • The reason the pandemic is not over is because SAGE says it’s not.

Categories
Opinion

Coronavirus: Why everyone was wrong – Dr. Beda Stadler

Professor Dr. Beda M Stadler is the former director of the Institute for Immunology at the University of Bern, a biologist and professor emeritus.

Novelty:

Sars-Cov-2 isn’t all that new, but merely a seasonal cold virus that mutated and disappears in summer, as all cold viri do — which is what we’re observing globally right now. Flu viri mutate significantly more, by the way, and nobody would ever claim that a new flu virus strain was completely novel.

Immunity:

In mid-April work was published by the group of Andreas Thiel at the Charité Berlin. A paper with 30 authors, amongst them the virologist Christian Drosten. It showed that in 34 % of people in Berlin who had never been in contact with the Sars-CoV-2 virus showed nonetheless T-cell immunity against it (T-cell immunity is a different kind of immune reaction, see below). This means that our T-cells, i.e. white blood cells, detect common structures appearing on Sars-CoV-2 and regular cold viri and therefore combat both of them.

…almost no children under ten years old got sick, everyone should have made the argument that children clearly have to be immune. For every other disease that doesn’t afflict a certain group of people, we would come to the conclusion that that group is immune. When people are sadly dying in a retirement home, but in the same place other pensioners with the same risk factors are left entirely unharmed, we should also conclude that they were presumably immune.

Modelling:

Epidemiologist also fell for the myth that there was no immunity in the population. They also didn’t want to believe that coronaviri were seasonal cold viri that would disappear in summer. Otherwise their curve models would have looked differently. When the initial worst case scenarios didn’t come true anywhere, some now still cling to models predicting a second wave.

Asymptomatic transmission:

The term “silent carriers” was conjured out of a hat and it was claimed that one could be sick without having symptoms.

The next joke that some virologists shared was the claim that those who were sick without symptoms could still spread the virus to other people…But for doctors and virologists to twist this into a story of “healthy” sick people, which stokes panic and was often given as a reason for stricter lockdown measures, just shows how bad the joke really is. At least the WHO didn’t accept the claim of asymptomatic infections and even challenges this claim on its website.

Testing:

So if we do a PCR corona test on an immune person, it is not a virus that is detected, but a small shattered part of the viral genome. The test comes back positive for as long as there are tiny shattered parts of the virus left. Correct: Even if the infectious viri are long dead, a corona test can come back positive, because the PCR method multiplies even a tiny fraction of the viral genetic material enough [to be detected]…The crux was that the virus debris registered with the overly sensitive test and therefore came back as “positive”. It is likely that a large number of the daily reported infection numbers are purely due to viral debris.

Kawasaki Syndrome:

If an infected person does not have enough antibodies, i.e. a weak immune response, the virus slowly spreads out across the entire body. Now that there are not enough antibodies, there is only the second, supporting leg of our immune response left: The T-cells beginn to attack the virus-infested cells all over the body. This can lead to an exaggerated immune response, basically to a massive slaughter; this is called a Cytokine Storm. Very rarely this can also happen in small children, in that case called Kawasaki Syndrome. This very rare occurrence in children was also used in our country to stoke panic. It’s interesting, however, that this syndrome is very easily cured. The [affected] children get antibodies from healthy blood donors, i.e. people who went through coronavirus colds.

Second Wave:

The virus is gone for now. It will probably come back in winter, but it won’t be a second wave, but just a cold.

Face masks:

Those young and healthy people who currently walk around with a mask on their faces would be better off wearing a helmet instead, because the risk of something falling on their head is greater than that of getting a serious case of Covid-19.

Lethality:

People below 65 years old make up only 0.6 to 2.6 % of all fatal Covid cases. To get on top of the pandemic, we need a strategy merely concentrating on the protection of at-risk people over 65.

https://medium.com/@vernunftundrichtigkeit/coronavirus-why-everyone-was-wrong-fce6db5ba809