Categories
News

Pfizer Reaps Hundreds of Millions in Profits From Covid Vaccine – The New York Times

The vaccine brought in $3.5 billion in revenue in the first three months of this year, nearly a quarter of its total revenue, Pfizer reported. The vaccine was, far and away, Pfizer’s biggest source of revenue.

On Tuesday, the company announced just how much money the shot is generating.

The vaccine brought in $3.5 billion in revenue in the first three months of this year, nearly a quarter of its total revenue, Pfizer reported. The vaccine was, far and away, Pfizer’s biggest source of revenue.

The company did not disclose the profits it derived from the vaccine, but it reiterated its previous prediction that its profit margins on the vaccine would be in the high 20 percent range. That would translate into roughly $900 million in pretax vaccine profits in the first quarter.

https://www.nytimes.com/2021/05/04/business/pfizer-covid-vaccine-profits.html

Categories
News

Denmark to cancel Johnson & Johnson coronavirus vaccine rollout, except on voluntary basis – RT

Danish authorities have opted for a more cautious path, even though Reuters reported that excluding J&J’s shot could significantly delay the country’s vaccination efforts.

Danish drug officials last month abandoned the use of AstraZeneca’s Covid-19 vaccine, also citing the risk of blood clots. In March, Denmark became the first country in the world to temporarily suspend the AstraZeneca shot, but unlike its European neighbors, the country made that suspension permanent.  

https://www.rt.com/news/522790-denmark-cancels-johnson-vaccine/

Categories
News

AstraZeneca vaccine: Does the AstraZeneca vaccine use mRNA? – The Express

Many of the vaccines developed to protect against COVID-19 are forms of messenger RNA (mRNA) vaccines.

The Moderna and Pfizer/BioNTech vaccines are forms of mRNA vaccine.

Unlike the Pfizer/BioNTech and Moderna coronavirus vaccines, the Oxford/AstraZeneca vaccine is not an mRNA vaccine.

Instead, the AstraZeneca vaccine is a viral vector vaccine made from a weakened form of a common cold virus from chimpanzees.

https://www.express.co.uk/life-style/health/1424769/astrazeneca-vaccine-does-astrazeneca-vaccine-use-mrna-evg

Categories
News

The shock and reality of catching COVID after being vaccinated – NPR

Robin Hauser, a pediatrician in Tampa, Florida, got COVID in February. What separates her from the vast majority of the tens of millions of other Americans who have come down with the virus is this: She got sick seven weeks after her second dose of the Pfizer-BioNTech vaccine.

https://www.pbs.org/newshour/health/the-shock-and-reality-of-catching-covid-after-being-vaccinated

Categories
Publications

COVID-19 mRNA Pfizer- BioNTech vaccine analysis print – UK Gov

All UK spontaneous reports received between 9/12/20 and 05/04/21 for COVID-19 vaccine mRNA Pfizer/BioNTech vaccine analysis print

https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/978316/050421_PF_DAP.pdf

Categories
Publications

The EMA covid-19 data leak, and what it tells us about mRNA instability – BMJ

Leaked documents show that some early commercial batches of Pfizer-BioNTech’s covid-19 vaccine had lower than expected levels of intact mRNA, prompting wider questions about how to assess this novel vaccine platform, writes Serena Tinari

https://www.bmj.com/content/372/bmj.n627

Categories
News

Germany ‘won’t approve’ AstraZeneca vaccine for over-65s – Independent

Germany has recommended the AstraZeneca coronavirus vaccine should only be given to people under the age of 65, according to reports.

The country’s vaccine committee has reportedly said the jab, developed alongside the University of Oxford, should only be offered to people aged between 18 and 64.

It gave a lack of sufficient data on the effectiveness of the inoculation in older people as the reason for the decision in a draft recommendation.

https://www.independent.co.uk/news/world/europe/astrazeneca-covid-vaccine-germany-elderly-b1794128.html

Categories
Publications

Anaphylaxis Following m-RNA COVID-19 Vaccine Receipt – CDC

  • December 9 – UK authorities confirmed 2 cases of anaphylaxis after vaccination
  • December 18*, 2020 – CDC has identified 6 case reports of anaphylaxis following Pfizer-BioNTech vaccine meeting Brighton Collaboration criteria for anaphylaxis
  • Persons with anaphylaxis following COVID-19 vaccination should not receive additional doses of COVID-19 vaccine

https://web.archive.org/web/20201219174137/https://www.cdc.gov/vaccines/acip/meetings/downloads/slides-2020-12/slides-12-19/05-COVID-CLARK.pdf

Categories
News

Hospital worker with no prior allergies in intensive care with severe reaction after Pfizer Covid vaccine – METRO

A hospital worker with no history of allergies was admitted to intensive care over a severe reaction she suffered 10 minutes after having Pfizer’s coronavirus vaccine. The unidentified female worker suffered an anaphylactic reaction shortly after receiving the injection at a hospital in Juneau, Alaska, on Tuesday.

Two healthcare workers in the UK suffered an anaphylactic reaction to the Pfizer injection after being given it last week, although the vaccine has been widely tested and analysed, with government experts in both the US and Great Britain deeming it safe.

https://web.archive.org/web/20201216200555/https://metro.co.uk/2020/12/16/hospital-worker-in-intensive-care-after-suffering-severe-allergic-reaction-to-covid-vaccine-13763695/

Categories
News

Dozens of GP practices in England opt out of Covid vaccine rollout – The Guardian


More than 100,000 patients will not be able to get the Covid vaccine from their family doctor after their GP surgeries decided not to take part in its deployment, the Guardian can reveal.

https://web.archive.org/web/20201211122855/https://www.theguardian.com/society/2020/dec/11/gp-practices-england-opt-out-covid-vaccine-rollout

Categories
News

Pfizer given protection from legal action by UK government – The Independent

The UK government has granted pharmaceutical giant Pfizer a legal indemnity protecting it from being sued, enabling its coronavirus vaccine to be rolled out across the country as early as next week.

The Department of Health and Social Care has confirmed the company has been given an indemnity protecting it from legal action as a result of any problems with the vaccine.

Ministers have also changed the law in recent weeks to give new protections to companies such as Pfizer, giving them immunity from being sued by patients in the event of any complications.

NHS staff providing the vaccine, as well as manufacturers of the drug, are also protected.

https://web.archive.org/web/20201202182311/https://www.independent.co.uk/news/health/coronavirus-pfizer-vaccine-legal-indemnity-safety-ministers-b1765124.html

Categories
Publications

Public needs to prep for vaccine side effects – Science

Most people will escape “severe” side effects, defined as those that prevent daily activity. Fewer than 2% of recipients of the Pfizer and Moderna vaccines developed severe fevers of 39°C to 40°C. But if the companies win regulatory approvals, they’re aiming to supply vaccine to 35 million people worldwide by the end of December. If 2% experienced severe fever, that would be 700,000 people.

Other transient side effects would likely affect even more people. The independent board that conducted the interim analysis of Moderna’s huge trial found that severe side effects included fatigue in 9.7% of participants, muscle pain in 8.9%, joint pain in 5.2%, and headache in 4.5%. In the Pfizer/BioNTech vaccine trial, the numbers were lower: Severe side effects included fatigue (3.8%) and headache (2%).

But that’s a higher rate of severe reactions than people may be accustomed to. “This is higher reactogenicity than is ordinarily seen with most flu vaccines, even the high-dose ones,” says Arnold Monto, an epidemiologist at the University of Michigan School of Public Health.

https://web.archive.org/web/20201126203444/https://science.sciencemag.org/content/370/6520/1022

Categories
News

The AstraZeneca Covid Vaccine Data Isn’t Up to Snuff – Wired

  • Vaccine produced by a partnership between a University of Oxford research institute, Vaccitech, and AstraZeneca, does not need to be stored at freezing temperatures.
  • Cheaper and easier to produce than the high-efficacy vaccines produced by BioNTech-Pfizer and Moderna.
  • The price of AstraZeneca’s shares dropped on the news, and an analysis from an investment bank concluded, “We believe that this product will never be licensed in the US.”
  • A closer look at the the Oxford-AstraZeneca trials reveals some very shaky science.
    • Cherry-picked the data
    • Dosing issues
    • Opaque planning and data analysis procedures
    • Age group selection

https://www.wired.com/story/the-astrazeneca-covid-vaccine-data-isnt-up-to-snuff/