EvidenceNotFear

Browse the articles related to this topic below.

Join our community on Guilded.

Why I spoke out against lockdowns – Professor Martin Kulldorff, Spiked

Post author By EvidenceNotFear
Post date 4 June 2021

I had no choice but to speak out against lockdowns. As a public-health scientist with decades of experience working on infectious-disease outbreaks, I couldn’t stay silent. Not when basic principles of public health are thrown out of the window. Not when the working class is thrown under the bus. Not when lockdown opponents were thrown to the wolves. There was never a scientific consensus for lockdowns. That balloon had to be popped.

…Ultimately, lockdowns protected young low-risk professionals working from home – journalists, lawyers, scientists, and bankers – on the backs of children, the working class and the poor.

https://www.spiked-online.com/2021/06/04/why-i-spoke-out-against-lockdowns/

Is Britain now a police state? Genuine question – Spiked

Post author By EvidenceNotFear
Post date 4 June 2021

We have become almost accustomed to this. To state censorship. To the police collaring people for what they say. Woke leftists are, despite all their bullshit, basically in favour of it, because the cops are on their side on these issues. Such is their historical illiteracy that they are completely chilled out about the state taking on the power to police speech.

https://www.spiked-online.com/2021/06/04/is-britain-now-a-police-state-genuine-question/

Tags Censorship, Civil Liberties, No Platformed, Police State, Spiked, Totalitarianism, UK, Woke

Dr David Bauer: ‘Pfizer vaccine produces fewer key antibodies’ – MSN News

Post author By EvidenceNotFear
Post date 4 June 2021

Dr Bauer of the Francis Crick Institute explains that the Pfizer vaccine produces 5-6 times fewer neutralising antibodies that play a key role in protecting us from the Indian variant. He suggests that booster Pfizer jabs will be essential.

https://www.msn.com/en-gb/news/other/dr-david-bauer-pfizer-vaccine-produces-fewer-key-antibodies/vi-AAKHPO1

Tags BioNTech, BNT162b2, Booster Immunisations, COVID-19, Dr. David Bauer, Francis Crick Institute, Indian Variant, Neutralising Antibodies, Pfizer, RT-PCR, SARS-CoV-2, Serological Response, Vaccination, Variant of Concern, Variants

‘Lockdown must end’: Sage expert warns that ‘awful’ curbs cannot last for ever… and says we must learn to live with Covid mutations – Daily Mail

Post author By EvidenceNotFear
Post date 4 June 2021

Lockdowns are ‘awful’ and Britain must learn to live with Covid without restrictions, one of the country’s most senior scientists has warned.

Sir Jeremy Farrar, director of the Wellcome Trust and a member of the Scientific Advisory Group for Emergencies (Sage), said the measures had had ‘very profound consequences’ on the nation’s mental health, education and jobs.

https://www.dailymail.co.uk/news/article-9649967/Sage-expert-warns-awful-curbs-ever.html

Tags Children, COVID-19, Daily Mail, Government, Lockdown, London School of Hygiene and Tropical Medicine, Mutation, Policy, Professor John Edmunds, SAGE, Sir Jeremy Farrar, The Wellcome Trust, UK, Vaccination, Variants

The Pentagon gave $39 MILLION to Dr. Peter Daszak’s EcoHealth Alliance – the charity that funded coronavirus research at the Wuhan lab accused of being the source of the outbreak, federal data reveals – Daily Mail

Post author By EvidenceNotFear
Post date 4 June 2021

Federal data seen by DailyMail.com reveals The Pentagon gave $39 million to EcoHealth Alliance, which funded a lab in Wuhan, China, between 2013 and 2020
The Wuhan Institute of Virology is accused of being the source of Covid-19
The majority of the DoD funding came from the DTRA, a military branch with a mission to ‘counter and deter weapons of mass destruction and improvised threat networks’
Federal grant data assembled by independent researchers shows that the charity has received more than $123 million from the government in total
Grants from the Pentagon included $6,491,025 from the Defense Threat Reduction Agency (DTRA) from 2017 to 2020
EHA also received $64.7 million from the US Agency for International Development (USAID)
It received $13 million from Health and Human Services, which includes the National Institutes of Health and Centers for Disease Control
It is not known how much of the money actually went to the Wuhan lab
EHA has also funded deeply controversial ‘gain of function’ experiments, where dangerous viruses are made more infectious to study their effect on human cells

https://www.dailymail.co.uk/news/article-9652287/The-Pentagon-funneled-39million-charity-funded-Wuhan-lab.html

‘New world order’ being formed before our eyes, Russia’s deputy defense minister tells RT ahead of key Moscow security conference – Colonel General Aleksandr Fomin, RT

Post author By EvidenceNotFear
Post date 3 June 2021

We are currently witnessing the formation of nothing less than a “new world order,” with the existing international legal system fracturing and states taking sides in a fresh Cold War, Russia’s deputy defense minister has told RT.

https://www.rt.com/russia/525561-new-world-order-emerges/

Tags Cold War, Colonel General Aleksandr Fomin, Geopolitics, New World Order, RT, Russia, The Great Reset, Warfare

Pfizer-BioNTech vaccine recipients have lower antibody levels targeting the Delta variant first discovered in India – The Francis Crick Institute

Post author By EvidenceNotFear
Post date 3 June 2021

Levels of antibodies in the blood of vaccinated people that are able to recognise and fight the new SARS-CoV-2 Delta variant first discovered in India (B.1.617.2) are on average lower than those against previously circulating variants in the UK, according to new laboratory data from the Francis Crick Institute and the National Institute for Health Research (NIHR) UCLH Biomedical Research Centre, published today (Thursday) as a Research letter in The Lancet.

The results also show that levels of these antibodies are lower with increasing age and that levels decline over time, providing additional evidence in support of plans to deliver a vaccination boost to vulnerable people in the Autumn.

https://www.crick.ac.uk/news/2021-06-03_pfizer-biontech-vaccine-recipients-have-lower-antibody-levels-targeting-the-delta-variant-first-discovered-in-india

Neutralising antibody activity against SARS-CoV-2 VOCs B.1.617.2 and B.1.351 by BNT162b2 vaccination – The Lancet

Post author By EvidenceNotFear
Post date 3 June 2021

In the case of single-dose recipients, our data show that NAbTs are significantly lower against B.1.617.2 and B.1.351 VOCs relative to B.1.1.7, implying that although a single dose might still afford considerably more protection than no vaccination, single-dose recipients are likely to be less protected against these SARS-CoV-2 variants. These data therefore suggest that the benefits of delaying the second dose, in terms of wider population coverage and increased individual NAbTs after the second dose,⁷ must now be weighed against decreased efficacy in the short-term, in the context of the spread of B.1.617.2. Worldwide, our data highlight the ongoing need to increase vaccine supply to allow all countries to extend second-dose protection as quickly as possible.

In the longer term, we note that both increased age and time since the second dose of BNT162b2 significantly correlate with decreased NAb activity against B.1.617.2 and B.1.351—both of which are also characteristic of the population in the UK at highest risk of severe COVID-19 (ie, older and vaccinated earlier), independent of other existing factors such as compromised immune status or comorbidity, or geographic-specific responses to vaccination.

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)01290-3/fulltext

Child vaccination implications for fully informed consent – HART

Post author By EvidenceNotFear
Post date 3 June 2021

HART continues to be deeply concerned to hear various MPs and SAGE representatives calling for children to be vaccinated against COVID-19 despite the lack of long-term safety data. Disturbing language has been used by teaching unions implying that the use of ‘peer pressure’ could be harnessed to boost take up among school children, even though such coercion would be unethical, not to mention contrary to UK and International Laws and Declarations.

Child vaccination — implications for fully informed consent

Tags Applied Behavioural Psychology, Behaviour Change, Coercion, COVID-19, Gillick Competency, Government, Green Book, Health Advisory and Recovery Team, Informed Consent, Law, Peer Pressure, Policy, Psychology, SAGE, Schools, Side-effects, Trials, UK, Vaccination

Lockdown ‘had no effect’ on coronavirus pandemic in Germany – The Telegraph

Post author By EvidenceNotFear
Post date 3 June 2021

A new study by German scientists claims to have found evidence that lockdowns may have had little effect on controlling the coronavirus pandemic.

Statisticians at Munich University found “no direct connection” between the German lockdown and falling infection rates in the country.

Instead, the study found infection rates had already clearly begun to fall before a national lockdown was imposed last November.

It also found clear evidence the rate was already falling on the two occasions the lockdown was tightened, in December and April.

https://www.telegraph.co.uk/news/2021/06/03/german-study-finds-lockdown-had-little-effect-virus-infections/

Tags Germany, Infection Rate, Lockdown, Munich University, R Value, The Telegraph

COVID-19 Vaccine Candidates and Abortion-Derived Cell Lines – Charlotte Lozier Institute

Post author By EvidenceNotFear
Post date 2 June 2021

Accurate information about the development and production of COVID-19 vaccines is essential, especially because many proposed candidates use newer molecular technologies for production of a viral vaccine. One concern regarding the ethical assessment of viral vaccine candidates is the potential use of abortion-derived cell lines in the development, production or testing of a vaccine. This analysis utilizes data from the primary scientific literature when available, along with data from clinical trial documents, reputable vaccine tracking websites, and published commercial information.1 It is the hope that by providing accurate data, recipients can make well-informed decisions regarding vaccine choices.

Analysis of SARS-CoV-2 (COVID-19) Vaccine Candidates *Last Updated 2 June 2021*					DOES NOT USE abortion-derived cell line DOES USE abortion-derived cell line SOME tests DO NOT use abortion-derived cells, SOME DO. � Currently undetermined
Sponsor(s)¹	Country	Strategy²	Clinical Trial Status³	Public Funding⁴	Design & Development	Production	Confirm-atory Lab Tests

WHOLE VIRUS VACCINE – LIVE ATTENUATED or INACTIVATED
Beijing Institute of Biological Products/ Sinopharm	China	Inactivated virus “BBIBP-CorV” Given: Intramuscular 2 doses (3 weeks apart)	WHO granted Emergency Use Listing (EUL) 7May2021 Early approval in China Phase 3 Phase 3		Vero monkey cells Wang et al., Cell 182, P713, 6Aug2020	Vero monkey cells Wang et al., Cell 182, P713, 6Aug2020	Cytopathic test Vero monkey cells Wang et al., Cell 182, P713, 6Aug2020
Wuhan Institute of Biological Products/ Sinopharm	China	Inactivated virus “New Crown COVID-19” Given: Intramuscular 2 doses (3 weeks apart)	Phase 3 Phase 3 Phase 3 Early approval in China Phase 1/2		Vero monkey cells Xia et al., JAMA 324, 951, 13Aug2020	Vero monkey cells Xia et al., JAMA 324, 951, 13Aug2020	Plaque reduction neutralization test Vero monkey cells Xia et al., JAMA 324, 951, 13Aug2020
Bharat Biotech/Indian Council of Medical Research	India	Inactivated virus “BBV152” Given: Intramuscular 2 doses (2 weeks apart)	India EUA granted Phase 3 Phase 3 Phase 1/2 Phase 1/2 Phase 1/2		Vero monkey cells Yadav et al., ResearchSquare 10Sept2020	Vero monkey cells Yadav et al., ResearchSquare 10Sept2020	Antibody ELISA Plaque reduction Vero monkey cellsYadav et al., ResearchSquare 10Sept2020
Institute of Medical Biology, Chinese Academy of Medical Sciences	China	Inactivated virus “SARS-CoV-2 vaccine” Given: Intramuscular 2 doses (2 weeks apart)	Phase 3 Phase 1/2 Phase 1/2		Vero monkey cells Pu et al., medRxiv, 6Oct2020	Vero monkey cells Pu et al., medRxiv, 6Oct2020	Antibody ELISA Neutralizing antibody cytopathic effect Vero monkey cells Pu et al., medRxiv, 6Oct2020 Supplement
John Paul II Medical Research Institute	USA	Live attenuated virus	Pre-clinical		Ethical cell lines as a matter of policy	Perinatal human cells (term umbilical cord and placental)	�
Research Institute for Biological Safety Problems	Kazakhstan	Inactivated virus “QazCovid-in” Given: Intramuscular 2 doses (3 weeks apart)	Phase 3 Phase 1/2		�	�	�
Sinovac Biotech Co., Ltd.	China	Inactivated virus “CoronaVac” Given: Intramuscular 2 doses (2 weeks apart)	WHO granted Emergency Use Listing (EUL) 1June2021 Phase 4 China granted conditional marketing authorization 8Feb2021 Chile, Brazil, Turkey, Indonesia EUA granted Phase 3 Early approval in China Phase 3 Phase 1/2 Phase 1/2 Phase 1/2		Vero monkey cells	Vero monkey cells Gao et al., Science 369, 77, 3July2020	protein test HEK293 cells Supplement Gao et al., Science 369, 77, 3July2020
Valneva and Dynavax	France USA UK	Inactivated Virus “VLA2001” plus adjuvant CpG1018 Given: Intramuscular 2 doses (3 weeks apart)	Phase 3 Phase 1/2		Vero monkey cells	Vero monkey cells Same platform as IXIARO, Valneva press release, 22April2020 Valneva COVID-19 – VLA2001	�

VIRAL VECTOR-BASED VACCINE
Altimmune	USA	Replication-deficient Adenovirus vector “AdCOVID” Given: Intranasal 1-2 doses	Phase 1/2		PER.C6 cells	PER.C6 cells Same platform as NasoVAX NasoVAX uses PER.C6 Licensed PER.C6 from Janssen
AstraZeneca University of Oxford	USA UK	Replication-deficient Adenovirus vector “AZD1222” “ChAdOX1nCoV-19” Given: Intramuscular 2 doses (4 weeks apart)	WHO granted Emergency Use Listing (EUL) on 15Feb2021 UK EUA granted India EUA granted Phase 3 Phase 3 Phase 3 Phase 3 Phase 2/3 Phase 2/3 Phase 1/2 Phase 1/2	Operation Warp Speed HHS-BARDA $1.2 Billion CEPI up to $384 Million	HEK293 cells	HEK293 cells van Doremalen et al., Nature, 30July2020	HEK293 cellsvan Doremalen et al., Nature, 30July2020 MRC-5 cells Almuqrin et al., ResearchSquare 20Oct2020
CanSino Biologics, Inc. Beijing Institute of Biotechnology, Academy of Military Medical Sciences, PLA of China	China	Replication-deficient Adenovirus vector “Ad5-nCoV” Given: Intramuscular 1 dose	EUA in Chile, Hungary, Pakistan, Mexico Phase 3 Phase 3 Phase 2 Phase 2 Phase 2 Phase 1 Phase 1		HEK293 cells	HEK293 cells Biospace, 12May2020
Gamaleya Research Institute	Russia	Replication-deficient Adenovirus vectors (rAd26-S+rAd5-S) “Gam-COVID-Vac” “Sputnik V” Given: Intramuscular 2 doses (3 weeks apart)	Phase 3 Phase 3 EUA in 39 countries as of Mar2021 Early approval in Russia August 2020 Phase 1/2 Phase 1/2		HEK293 cells	HEK293 cells Gamaleya has not published details on this vaccine, but has posted information on use of cell lines for their other adenoviral vaccines
ImmunityBio and NantKwest	USA	Replication-deficient Adenovirus vector recombinant “hAd5 S-Fusion + N-ETSD” Given: Subcutaneous	Phase 1/2 Phase 1/2 Phase 1 Phase 1 Phase 1		E.C7 cells (derivative of HEK293 cells) Rice et al., bioRxiv 30July2020	E.C7 cells (derivative of HEK293 cells) Rice et al., bioRxiv 30July2020	Protein and antibody tests HEK293T cells Rice et al., bioRxiv 30July2020 Seiling et al., medRxiv 6Nov2020
Institut Pasteur and Themis and Merck	USA France	Replication-competent recombinant measles virus “TMV-083” Given: Intramuscular	Development Discontinued Phase 1/2Phase 1	CEPI up to $4.9 Million	HEK293T Development and rescue of recombinant measles virus Hörner et al., PNAS 22Dec2020 Hörner et al. Supplement “SARS-CoV-2 S-encoding vaccine candidates… were generated as described previously”	Vero monkey cells Hörner et al., PNAS 22Dec2020 Hörner et al. Supplement	Lentiviral vectors for antigenic DCFusogenic testHEK293TFusogenic testS protein expressionVero monkey cellsHörner et al., PNAS 22Dec2020 Hörner et al. Supplement
Israel Institute for Biological Research (IIBR)	Israel	Replication-competent recombinant vesicular stomatitis virus (VSVΔG) “IIBR-100” Given: Intramuscular1 dose	Phase 1/2		BHK hamster cells Vero monkey cells Yahalom-Ronen et al., bioRxiv 19June2020	Vero monkey cells Yahalom-Ronen et al., bioRxiv 19June2020	Plaque reduction; immunofluorescence Vero monkey cells Yahalom-Ronen et al., bioRxiv 19June2020
Janssen Research & Development, Inc. Johnson & Johnson	USA	Replication-deficient Adenovirus vector “Ad26.COV2-S” Given: Intramuscular 1 dose (some trials use 2 doses, 8 weeks apart)	FDA Emergency Use Authorization Approved Phase 3 Phase 3 Phase 1/2	Operation Warp Speed HHS-BARDA $1,457,887,081 total	PER.C6 cells	PER.C6 cells Tostanoski et al., Nature Medicine, 3Sept2020; J&J, 30March2020; Janssen Vaccine Technologies
Laboratorio Avi-Mex	Mexico	Live recombinant Newcastle Disease Virus Expressing spike-fusion chimeric protein “Patria” Given: Intramuscular or Intranasal	Phase 1		Bacterial cells BSRT7 hamster cells Per Sun et al., Vaccines 17Dec2020	� Chicken eggs Per Sun et al., Vaccines 17Dec2020	� Neutralization Assay Vero monkey cells Per Sun et al., Vaccines 17Dec2020
Meissa Vaccines, Inc.	USA	Live attenuated recombinant RSV viral vector “MV-014-210” Given: Intranasal 1-3 doses (5 weeks apart)	Phase 1			Vero monkey cells Spike expressing, Based on recombinant RSV platform	�
Rega Institute, KU Leuven	Belgium	Replication-competent attenuated yellow fever vaccine (YF17D) vector “YF-S0” Given: Intramuscular 1 dose	Pre-clinical		BHK-21J hamster cells Sanchez-Felipe et al., Nature, 1Dec2020	BHK-21J hamster cells Sanchez-Felipe et al., Nature, 1Dec2020	Antibody titer Pseudovirus HEK293T cells Immunoblot BHK-21J hamster cells Sanchez-Felipe et al., Nature, 1Dec2020
ReiThera	Italy	Replication-deficient simian adenovirus encoding S “GRAd COV2” Given: Intramuscular 1 dose	Phase 2/3 Phase 1		HEK293T cells Development and rescue of recombinant Capone et al., bioRxiv 22Oct2020	HEK293T cells Capone et al., bioRxiv 22Oct2020	HEK293T cells Capone et al., bioRxiv 22Oct2020
Merck and IAVI	USA	Replication-competent recombinant vesicular stomatitis virus (VSVΔG) “V590” Given: Intramuscular	Development Discontinued Phase 1	Operation Warp Speed HHS-BARDA $38,033,570	Vero monkey cells	Vero monkey cells Use rVSV Ervebo platform Ervebo uses Vero cell culture-11 Description	�
Shenzhen Geno-immune Medical Institute	China	Lentivirus minigenes + Adult human APC (antigen-presenting cells) “COVID-19/aAPC” Given: Subcutaneous 3 doses (2 weeks apart)	Phase 1		�		�
Shenzhen Geno-immune Medical Institute	China	Lentivirus minigenes + Adult human CD/T cells (dendritic cells and T cells) “LV-SMENP-DC” Given: Subcutaneous and Intravenous 1 dose	Phase 1/2		�		�
Vaxart	USA	Replication-deficient Adenovirus vector “VXA-CoV2-1” plus dsRNA adjuvant Given: Oral 2 doses (4 weeks apart)	Phase 1		HEK293 cells	HEK293 cells Moore et al., bioRxiv 6Sept2020
PROTEIN-BASED VACCINE
Anhui Zhifei Longcom Biopharmaceutical/Institute of Microbiology, Chinese Academy of Sciences	China	Protein vaccine Recombinant RBD dimer plus adjuvant ”ZF2001” Given: Intramuscular 2 or 3 doses (28 days apart)	Phase 3 Phase 2 Phase 1/2 Phase 1		HEK293T cells Dai et al., Cell 6Aug2020	CHO hamster cells Dai et al., Cell 6Aug2020	Pseudovirus HEK293T cells Dai et al., Cell 6Aug2020
Clover Biopharmaceuticals, Inc.	China	Protein vaccine “SCB-2019” plus adjuvant CpG 1018 Given: Intramuscular 2 doses (3 weeks apart)	Phase 2/3 Phase 1	CEPI up to $69.5 Million	cDNA in expression vector; transfect CHO hamster cells Liang et al., bioRxiv, 24Sept2020 Trimer-Tag system; Liu et al., Scientific Reports 2017	CHO hamster cells Trimer-Tag system; Liu et al., Scientific Reports 2017	PseudovirusHEK293 cellsRef’d: Nie et al., Emerging Microbes & Infections 24Mar2020Cytopathic effect Vero monkey cellsLiang et al., bioRxiv, 24Sept2020
COVAXX and United Biomedical	USA Taiwan	Protein vaccine “UB-612” S1-RBD-protein; Multitope Peptide-Based Vaccine (MVP) Given: Intramuscular 2 doses (4 weeks apart)	Phase 2/3 Phase 1		cDNA in expression vector; transfect CHO hamster cells Guirakhoo et al., bioRxiv, 30Nov2020	CHO hamster cells Guirakhoo et al., bioRxiv, 30Nov2020	Antibody blocked binding to hACE2 HEK293 Guirakhoo et al., bioRxiv, 30Nov2020
Federal Budgetary Research Institution State Research Center of Virology and Biotechnology “Vektor”	Russia	Protein vaccine “EpiVacCorona” chemically synthesized peptide antigens of SARS-CoV-2, conjugated to a carrier protein adsorbed on an aluminum-containing adjuvant Given: Intramuscular2 doses (3 weeks apart)	Phase 3 Early approval in Russia Oct 2020 Phase 1/2		�	chemically synthesized peptide antigens	�
Instituto Finlay de Vacunas	Cuba	Protein vaccine “Finlay-FR-1” (“Soberana 01”) Receptor-binding domain (RBD) SARS-CoV-2 spike + adjuvant Given: Intramuscular2 doses (4 weeks apart)	Phase 1/2 Phase 1		� RBD produced in mammalian cells Garcia-Rivera, MEDICC Review, 30Oct2020	� RBD produced in mammalian cells Garcia-Rivera, MEDICC Review, 30Oct2020	�
Instituto Finlay de Vacunas	Cuba	Protein vaccine “Finlay-FR-2” (“Soberana 02”) Receptor-binding domain (RBD) SARS-CoV-2 spike chemically bound tetanus toxoid + adjuvant Given: Intramuscular2 doses (4 weeks apart)	Phase 2 Phase 1		� RBD produced in mammalian cells Garcia-Rivera, MEDICC Review, 30Oct2020	� RBD produced in mammalian cells Garcia-Rivera, MEDICC Review, 30Oct2020	�
John Paul II Medical Research Institute	USA	Recombinant Protein Perinatal human cells (term umbilical cord and placental)	Pre-clinical		Ethical cell lines as a matter of policy	Perinatal human cells (term umbilical cord and placental)	�
Kentucky BioProcessing, Inc. (British American Tobacco)	USA	Protein vaccine “KBP-201” Plant-expressed RBD Given: Intramuscular2 doses (3 weeks apart)	Phase 1/2		Recombinant DNA sequence for RBD of SARS-CoV-2	Plant expression of RBD peptide	�
Medicago	Canada	Protein on Virus-Like Particle “CoVLP” Plant-expressed spike protein particle with adjuvant, CpG1018 or AS03 Given: Intramuscular 2 doses (3 weeks apart)	Phase 2/3 Phase 2 Phase 1		Recombinant DNA sequence in Agrobacterium, transformation of plant cells	Plant expression of protein and VLP Ward et al., medRxiv 6Nov2020	Pseudovirus HEK293 cells Ward et al., medRxiv 6Nov2020
Migal Galilee Research Institute	Israel	Protein vaccine E. coli expressed chimeric S and N proteins Given: Oral	Pre-clinical		�	Bacterial production system MigVax’s corona subunit vaccine	�
Novavax	USA	Protein vaccine “NVX-CoV2373” Baculovirus expression plus Matrix M adjuvant Given: Intramuscular 2 doses (3 weeks apart)	Phase 3 Phase 3 Phase 2 Phase 1	Operation Warp Speed HHS-BARDA $1,600,434,523 CEPI up to $388 Million		Sf9 insect cells Bangaru et al., Science, 27Nov2020 Bangaru et al., Supplement Bangaru et al., bioRxiv preprint, 6Aug2020; Graphical view	Pseudovirus HEK293 cells Bangaru et al., Science, 27Nov2020 Bangaru et al., Supplement Bangaru et al., bioRxiv preprint, 6Aug2020
Sanofi and GSK Protein Sciences	USA France	Protein vaccine Baculovirus expression plus AS03 adjuvant Given: Intramuscular 2 doses (3 weeks apart)	Phase 3 Phase 2 Phase 1/2	Operation Warp Speed HHS-BARDA $2,072,775,336 total	Recombinant baculovirus Francica et al., bioRxiv 2Mar2021	Sf9 insect cells Francica et al., bioRxiv 2Mar2021 Baculovirus expressed recombinant protein	Pseudovirus HEK293T cells Francica et al., bioRxiv 2Mar2021
Sorrento	USA	Protein vaccine “T-VIVA-19” SARS-Cov-2 spike protein S1 domain fused with human IgG-Fc Given: Intramuscular	Pre-clinical			CHO cells Herrmann et al., bioRxiv preprint, 30June2020	Antibody ELISA; Neutralization assays Vero monkey cells Herrmann et al., bioRxiv preprint, 30June2020
Sorrento	USA	Protein vaccine “STI-6991” SARS-Cov-2 spike protein expressed on K562 cells	Pre-clinical		�	K562 cells Concept: Ji et al., Medicine in Drug Discovery March2020	�
University of Pittsburgh	USA	Protein vaccine Adenovirus-expressed recombinant proteins “PittCoVacc” Given: Microneedle arrays	Pre-clinical		HEK293 cells	HEK293 cells Kim et al., EBioMedicine , 2April2020
University of Queensland and CSL Ltd.	Australia	Protein vaccine “V451” Recombinant protein with proprietary molecular clamp Given: Intramuscular	HALTED Phase 1 Phase 1 Phase 1	CEPI up to $4.5 Million		expiCHO hamster cells	�
Walter Reed Army Institute of Research (WRAIR) / U.S. Army Medical Research and Development Command	USA	Protein vaccine ”SpFN” Spike-Ferritin nanoparticle with ALFQ adjuvant Given: Intramuscular 2-3 doses (4 weeks apart; plus 6 months after initial injection)	Phase 1		Expi293 cells Carmen et al., bioRxiv 28April2021	Expi293 cells Carmen et al., bioRxiv 28April2021	Pseudovirus HEK293 cells Virus neutralization Vero monkey cells Joyce et al., bioRxiv 25Mar2021 & Supplement

RNA VACCINE
Arcturus Therapeutics	USA	mRNA vaccine self-transcribing, replicating “LUNAR-CoV19” (“ARCT-021”) in vitro transcription reaction with T7 RNA polymerase from STARR plasmid template LUNAR proprietary lipid nanoparticle encapsulated Given: Intramuscular 1 dose	Phase 2 Phase 2 Phase 1/2		Sequence designed on computer	No cells used de Alwis et al., bioRxiv 3Sept2020	protein test HEK293 Protein expression Hep3b cells Plaque reduction neutralization Vero monkey cells de Alwis et al., bioRxiv 3Sept2020
CureVac	Germany	mRNA vaccine non-replicating “CVnCoV” in vitro transcription lipid nanoparticle encapsulated Given: Intramuscular 2 doses (4 weeks apart)	Phase 3 Phase 2/3 Phase 2 Phase 1	CEPI up to $15.3 Million	Sequence designed on computer	No cells used Rauch et al., bioRxiv 9Feb2021	Protein test Reticulocyte lysate, HeLa cells Rauch et al., bioRxiv 9Feb2021
Imperial College London	UK	mRNA vaccine Self-amplifying ”LNP-nCoVsaRNA” in vitro transcription lipid nanoparticle encapsulated Given: Intramuscular 2 doses	Phase 1		Expression plasmid HEK293 cells McKay et al., bioRxiv 25April2021	No cells used McKay et al., bioRxiv 25April2021	Pseudovirus HEK293T cells McKay et al., bioRxiv 25April2021
Moderna, Inc. with National Institutes of Health	USA	mRNA vaccine non-replicating “mRNA-1273” T7 RNA polymerase-mediated transcription from DNA plasmid template LNP (lipid nanoparticle) encapsulated Given: Intramuscular 2 doses (4 weeks apart)	*FDA Emergency Use Authorization Approved* Phase 3 Phase 2 Phase 1	Operation Warp Speed HHS-BARDA $2,479,894,979 total CEPI up to $1 Million	Sequence designed on computer	No cells used Corbett et al., Nature , 5Aug2020	protein test & pseudovirus HEK293 cells Plaque reduction neutralization Vero monkey cells Corbett et al., Nature , 5Aug2020
Pfizer and BioNTech	USA Germany	mRNA vaccine non-replicating “BNT-162a1,b1,b2,b3,c2” nucleoside-modified mRNA in vitro transcribed by T7 polymerase from a plasmid DNA template LNP (lipid nanoparticle) encapsulated Given: Intramuscular 2 doses (3 weeks apart)	*FDA Emergency Use Authorization Approved* UK EUA granted Phase 2/3 Phase 1/2 Phase 1/2 Phase 1 Phase 1	Operation Warp Speed HHS-BARDA $1.95 Billion	Sequence designed on computer	No cells used Vogel et al., bioRxiv 8Sept2020	protein test & pseudovirus HEK293 cells Neutralization assay Vero monkey cells Vogel et al., bioRxiv 8Sept2020
Providence Therapeutics	Canada	mRNA vaccine “PTX-COVID19-B” mRNA in vitro transcription from plasmid template using T7 RNA polymerase LNP (lipid nanoparticle) encapsulated Given: Intramuscular 2 doses (4 weeks apart)	Phase 1		HEK293T cells used to select mRNA candidate Liu et al., bioRxiv 12May2021	No cells used Cision, 5Aug2020 Providence Therapeutics Liu et al., bioRxiv 12May2021	Pseudovirus, serum neutralization HEK293T cells Vero monkey cells Liu et al., bioRxiv 12May2021
Sanofi Pasteur and Translate Bio	USA France	mRNA vaccine non-replicating “MRT5500” synthesized by in vitro transcription employing RNA polymerase with a plasmid DNA template LNP (lipid nanoparticle) encapsulated Given: Intramuscular 2 doses (3 weeks apart)	Phase 1/2		HEK293T cells used to select mRNA candidate Kalnin et al., npj Vaccines 19Apr2021	No cells used Kalnin et al., npj Vaccines 19Apr2021 Kalnin et al., bioRxiv 14Oct2020 mRNA production in the lab ; Translate Bio scientific platform	protein test & pseudovirus HEK293 cells Kalnin et al., npj Vaccines 19Apr2021 Kalnin et al., bioRxiv 14Oct2020

DNA VACCINE
Genexine	Korea	DNA vaccine “GX-19” DNA synthesized in vitro, placed in plasmid vector Given: Intramuscular and Electroporation 2 doses (4 weeks apart)	Phase 1/2 Phase 1/2		Sequence designed on computer	No cells used Seo et al., Vaccines 24March2021	No cells used Seo et al., Vaccines 24March2021
Inovio Pharmaceuticals	USA	DNA vaccine “INO-4800” DNA synthesized in vitro, placed in plasmid vector Given: Intradermal Electroporation 2 doses (4 weeks apart)	Phase 2/3 Phase 2 Phase 1/2 Phase 1	Operation Warp Speed CEPI up to $22.5 Million	Sequence designed on computer	No cells used Smith et al., Nature 20May2020	protein test & pseudovirus HEK293 cells Smith et al., Nature 20May2020
Osaka University, AnGes, Takara Bio	Japan	DNA vaccine “AG0301-COVID19” “AG0302-COVID19” Chemically synthesized plasmid vector grown in E. coli Pressure injector Given: Intramuscular 2 doses (2 weeks apart)	Phase 2/3 Phase 1/2 Phase 1/2		Sequence designed on computer	No cells used E. coli</em Nishikawa et al., bioRxiv, 14Jan2021	Virus neutralization Vero E6 cells monkey cells Nishikawa et al., bioRxiv, 14Jan2021
Symvivo Corporation	Canada	DNA vaccine “bacTRL-spike” Genetically engineered Bifidobacterium longum Given: Oral, bacteria bind to gut lining 1 dose	Phase 1		�	No cells used	�
Zydus Cadila	India	DNA vaccine “ZyCov-D” Chemically synthesized plasmid vector grown in E. coli Given: Intramuscular 3 doses (4 weeks apart)	Phase 3 Phase 1/2		Sequence designed on computer	No eukaryotic cells used E. coli</em Dey et al., bioRxiv, 26Jan2021	Expression analysis Plaque reduction Vero cells monkey cells Dey et al., bioRxiv, 26Jan2021 Yadav et al., bioRxiv, 3Feb2021

http://archive.today/2022.06.16-202534/https://lozierinstitute.org/update-covid-19-vaccine-candidates-and-abortion-derived-cell-lines/

Tags Aborted Fetal Cells, Abortion, BNT162b2, Charlotte Lozier Institute, COVID-19, Fetal Cells, HEK293T, Johnson & Johnson, Moderna, mRNA, PER.C6, Pfizer, Research, Vaccination, WI-38

Nearly 40 per cent of recent Covid victims died primarily of other conditions – The Telegraph

Post author By EvidenceNotFear
Post date 2 June 2021

Nearly 40 per cent of recently registered Covid deaths in England and Wales were people who died primarily from another condition, latest figures from the Office for National Statistics (ONS) show.

Out of 107 Covid deaths registered in the week ending May 21, just 66 had coronavirus recorded as the underlying cause of death, 61.7 per cent.

https://www.telegraph.co.uk/news/2021/06/02/nearly-40-per-cent-recent-covid-victims-died-primarily-conditions/

Tags AstraZeneca, Cases, Cause of Death, COVID-19, Death Registration, Office for National Statistics, Sir John Bell, Statistics, The Telegraph, UK, Vaccination, WHO

Covid Whistleblower Service: Francis Hoar Launches the Covid19 Assembly’s “Speak Out” Service – Covid19 Assembly

Post author By EvidenceNotFear
Post date 2 June 2021

The ‘Speak Out’ service is available to witnesses with information about ALL aspects of the pandemic response, not just Covid death reporting. Professional legal advice will be given free-of-charge* to eligible applicants at the start of their process and everything will be fully confidential. Those with information on any Covid related practices of concern are encouraged to come forward as a matter of urgency by completing the form on the “Speak Out” page of the website below.

Go to the Covid19 Assembly Speak Out Service

Tags Auditing, COVID-19, Covid19 Assembly, Francis Hoar, Government, Law, Liability, Policy, Whistleblowers

UK reports no new COVID-19 deaths for first time since March 2020 – Reuters

Post author By EvidenceNotFear
Post date 1 June 2021

Britain recorded no new deaths within 28 days of a positive COVID-19 test on Tuesday.

The last time Britain recorded no deaths was in March 2020, before the country had entered its first lockdown. The figure on Tuesday relates to how many deaths have been reported and it comes after a national holiday on Monday – a factor which has in the past skewed the data.

…Britain’s overall death toll from the pandemic stands at 127,782 and is the fifth highest in the world, according to Johns Hopkins University data.

https://www.reuters.com/world/uk/uk-reports-no-new-covid-19-deaths-3165-new-infections-2021-06-01/

Tags Cases, COVID-19, Daily Deaths, Death Registration, Johns Hopkins University, Reuters, Statistics, UK

Peter Hitchens: The Slow Death of Freedom 1914-2020 – Unlocked

Post author By EvidenceNotFear
Post date 1 June 2021

In a hard-hitting interview, Peter Hitchens argues that through Covid we have surrendered our liberty to the state, perhaps irretrievably.

Tags Civil Liberties, COVID-19, History, Lockdown, Peter Hitchens, Politics, UK, Unlocked, World War 1, World War 2

Miscarriages of justice under coronavirus laws ‘going unchallenged’ as court hearings bypassed – The Independent

Post author By EvidenceNotFear
Post date 1 June 2021

Hundreds of people may have been wrongly convicted of coronavirus offences under a controversial system that bypasses court hearings, analysis by The Independent suggests.

Thousands of charges for allegedly breaching lockdown restrictions and rules around gatherings have been processed under the Single Justice Procedure, which sees one magistrate decide cases based largely on police evidence.

https://www.independent.co.uk/news/uk/home-news/coronavirus-fines-laws-letters-court-prosecution-b1856653.html

Tags Civil Liberties, COVID-19, Crown Prosecution Service, Health Protection Regulations, Law, Single Justice Procedure, The Coronavirus Act 2020, UK, Wrongful Convictions

Release Us From This Servitude – James Delingpole & Toby Young, London Calling

Post author By EvidenceNotFear
Post date 31 May 2021

Fresh from their smash reunion tour this weekend, James and Toby recap the weekend’s anti-lockdown march that wound from Parliament Square to Toby’s doorstep.

We then parse the testimony of the PM’s former “top man,” Dominic Cummings, before the House’s Health and Science select committees last week and who came out of it better. Do you want a Prime Minister or a Monarch (and by “monarch” we’re not talking about the one we’ve already got.)

https://ricochet.com/podcast/london-calling/release-us-from-this-servitude/

Tags AstraZeneca, COVID-19, Dr. Soumya Swaminathan, Financial Incentives, Government, James Delingpole, London Calling, Pfizer, Pharmaceutical Industry, Policy, Protests, Sir Patrick Vallance, Toby Young, Vaccination, Vaccine Damage, Vaccine Hesitancy, WHO

History shows us why vaccines must be voluntary – Spiked

Post author By EvidenceNotFear
Post date 31 May 2021

To this day, many commentators think that coercion is justified in defence of public health. Arguments over ‘vaccine passports’ and obligations to get vaccinated in contracts of employment are already raging. The voluntary principle, however, is a good one. It is what allowed Britain’s vaccination programme to move beyond the controversies of the 1880s, squaring the circle of vaccination and opposition by letting people opt out. Pointedly, the conscientious objection clause over time killed off Britain’s anti-vaccine campaigns by removing the causes célèbres of vaccine martyrdom.

https://www.spiked-online.com/2021/05/31/history-shows-us-why-vaccines-must-be-voluntary/

Domestic vaccine passport plans set to be scrapped by government, report says – The Telegraph

Post author By EvidenceNotFear
Post date 31 May 2021

Plans for the use of Covid-19 passports as a legal requirement for entry to large events this summer are set to be dropped, according to a report.

Officials working on the ongoing Covid-19 status certification review do not believe that the law will be changed to mandate their use in the UK, with one government source claiming that the plans were “dead”, The Telegraph reported.

“It’s not a case of ‘it’s finely balanced’. It’s not going to happen,” the source told the newspaper.

https://www.independent.co.uk/news/uk/politics/vaccine-passports-covid-certificates-review-b1856770.html

Tags Civil Liberties, COVID-19, Equality and Human Rights Commission, Government, New Normal, Policy, Testing, The Cabinet Office, The Telegraph, Travel, UK, Vaccination, Vaccine Passports

The smearing of anti-lockdown protests – Spiked

Post author By EvidenceNotFear
Post date 30 May 2021

The ‘Unite for Freedom’ anti-lockdown protest in London yesterday was as good-natured and peaceful as the previous anti-lockdown protests I have reported on for spiked. Seeing the sculpture and words was a gladdening moment on a day blessed by sunshine.

…The coverage from major news agencies and outlets told the story of ‘hundreds’ of ‘anti-vaxxers’. ‘Hundreds’ is the downplaying part. It worries me. I was there, and I know it is not true. Do I need to see the news unfold with my own eyes every time in order to fact-check the front pages?

I can’t estimate the numbers because the scale of the crowd was too vast, and moved steadily for many hours through the streets of London. Tens of thousands? Hundreds of thousands? Presumably the Met Police could estimate if they wanted to. The Guardian at least reported ‘vast numbers of people’. The Press Association declared, ‘Hundreds join anti-vaccination protest in central London’. The comments put that misconception straight.

https://www.spiked-online.com/2021/05/30/the-smearing-of-anti-lockdown-protests/

Tags Applied Behavioural Psychology, Behaviour Change, Civil Liberties, COVID-19, Freedom, Government, Hysteria, London, Media, Misinformation, Nudging, pass, Policy, Protests, Spiked, UK, Unite for Freedom, Vaccine Hesitancy, Vaccine Passports