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Publications

Why Most Clinical Research Is Not Useful – Prof. John Ioannidis

Many clinical research studies, even in the major general medical journals, do not satisfy the identifiable features that make them useful. These features include:

  • problem base;
  • context placement;
  • information gain;
  • pragmatism;
  • patient centeredness;
  • value for money;
  • feasibility;
  • transparency.

Most clinical research findings false. Further, most of the true findings do not result in huge human benefit. Reform and improvement in the clinical research are overdue.

See also: Peer review: a flawed process at the heart of science and journals by Richard Smith at the Journal of the Royal Society of Medicine

Quoted summary points

Blue-sky research cannot be easily judged on the basis of practical impact, but clinical research is different and should be useful. It should make a difference for health and disease outcomes or should be undertaken with that as a realistic prospect.

Many of the features that make clinical research useful can be identified, including those relating to problem base, context placement, information gain, pragmatism, patient centeredness, value for money, feasibility, and transparency.

Many studies, even in the major general medical journals, do not satisfy these features, and very few studies satisfy most or all of them. Most clinical research therefore fails to be useful not because of its findings but because of its design.

The forces driving the production and dissemination of nonuseful clinical research are largely identifiable and modifiable.

Reform is needed. Altering our approach could easily produce more clinical research that is useful, at the same or even at a massively reduced cost.

https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1002049

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News Opinion

The data is in – stop the panic and end the total isolation – Dr. Scott Atlas

Five key facts are being ignored by those calling for continuing the near-total lockdown.

Fact 1: The overwhelming majority of people do not have any significant risk of dying from COVID-19.

Fact 2: Protecting older, at-risk people eliminates hospital overcrowding.

Fact 3: Vital population immunity is prevented by total isolation policies, prolonging the problem.

Fact 4: People are dying because other medical care is not getting done due to hypothetical projections.

Fact 5: We have a clearly defined population at risk who can be protected with targeted measures.

https://thehill.com/opinion/healthcare/494034-the-data-are-in-stop-the-panic-and-end-the-total-isolation

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News Videos

No scientific proof social distancing prevents spread of COVID-19 – Professor Joel Hay, USC

  • COVID-19 is very infectious but causes no symptoms in most people.
  • New York disaster is due to use of ventilators.
  • 80% of pregnant women were COVID-19 positive but not a single baby died due to COVID-19.
  • Do what we always do: isolate the frail and sick but don’t isolate the young and healthy.
  • Getting herd immunity is how we’ve solved the problem in the past.
  • Social distancing is destroying millions of lives and killing 100 people for every one it saves.

Visit Professor Joel Hay’s site at: https://joelhay.com/

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News

Expert argues Britain’s crisis peaked before lockdown; fatality rate could be as low as 0.1% – Daily Mail

Oxford University Professor Carl Heneghan: UK’s outbreak peaked in March before lockdown but ministers had ‘lost sight’ of the scientific evidence and panicked.

https://www.dailymail.co.uk/news/article-8235979/UKs-coronavirus-crisis-peaked-lockdown-Expert-argues-draconian-measures-unnecessary.html


See coverage from 21st Century Wire: REVEALED: UK Ministers Knew Crisis Had Peaked Before Lockdown, But Panicked Anyway

See videos from Andrew Mather of who has been showing this by analysing WHO reports.

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Videos

Perspectives on the Pandemic | Dr. John Ioannidis Update: 4.17.20 | Episode 4

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Publications Videos

COVID-19 lethality in 0.12% to 0.2% which is in the range of severe influenza – medRxiv

Stanford University study founds antibodies in 50 to 85 times more people than previously thought in Santa Clara County, California. Covid-19 lethality of 0.12% to 0.2% which is in the range of severe influenza. 

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News

The lockdown is NOT a way of beating this virus – Dr. Malcolm Kendrick

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News Videos

Perspectives on the Pandemic | Dr. David L. Katz | Episode 3

  • 00:58-How to minimize the risk of COVID-19
  • 03:52-Comparing the responses to a global pandemic
  • 08:53-Who is most at risk
  • 13:44-Is our global response warranted?
  • 17:17-Comparing COVID-19 to the flu
  • 20:55-Is the risk really that high?
  • 23:53-What is the fatality rate versus other common risk factors?
  • 25:2900:58-How to minimize the risk of COVID-19
  • 03:52-Comparing the responses to a global pandemic
  • 08:53-Who is most at risk
  • 13:44-Is our global response warranted?
  • 17:17-Comparing COVID-19 to the flu
  • 20:55-Is the risk really that high?
  • 23:53-What is the fatality rate versus other common risk factors? 25:29-The risk of labeling COVID-19 as a ?pandemic?
  • 26:14-Are the COVID-19 tests reliable?
  • 28:58-Should we be concerned about herd immunity?
  • 30:16-On the chances of getting a vaccine
  • 31:47-The return of ?measles parties??
  • 34:30-Breaking down the pros and cons of herd immunity
  • 37:25-Is lockdown making the problem worse?
  • 40:01-How to really hashtag Flatten the Curve
  • 45:45-Can we really trace the exposure for every person?
  • 48:06-Is authoritarianism growing in the name of public health? 50:37-Who can we trust when this pandemic is over?
  • 54:54-Industries? roles in the pandemic
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Publications

Population-level COVID-19 mortality risk for non-elderly individuals overall and for non-elderly individuals without underlying diseases in pandemic epicenters – medRxiv

 CONCLUSIONS: People <65 years old have very small risks of COVID-19 death even in pandemic epicenters and deaths for people <65 years without underlying predisposing conditions are remarkably uncommon. Strategies focusing specifically on protecting high-risk elderly individuals should be considered in managing the pandemic.

COVID-19 is largely harmless to the general population under 65 with no pre-existing conditions, who are more likely to die in a road accident.

https://www.medrxiv.org/content/10.1101/2020.04.05.20054361v2

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Videos

Professor Knut Wittkowski: Covid19 epidemic is already declining in many countries

Professor Knut Wittkowski argues that lockdowns are counterproductive. The COVID-19 epidemic is already declining or even already over in many countries.

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Videos

Social distancing & lockdown will create the second wave of COVID-19 – Professor Knut Wittkowski

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News

Lockdown will kill more people than the virus says former Israeli Health Minister

https://en.globes.co.il/en/article-lockdown-lunacy-1001322696

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Videos

Questioning Conventional Wisdom in the COVID-19 Crisis, with Dr. Jay Bhattacharya – The Hoover Institution

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News

Is Our Fight Against Coronavirus Worse Than the Disease? – The New York Times

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Videos

Perspectives on the Pandemic | Dr John Ioannidis of Stanford University | Interview

This video has been removed by YouTube so a Bitchute mirror is provided below. Please wait after pressing the play button. It may take longer than usual to load the video.

  • 00:50-Dr. Ioannidis summarizes his article titled “A fiasco in the making? As the coronavirus pandemic takes hold, we are making decisions without reliable data” (linked below)
  • 03:47-The truth about COVID-19’s death rate
  • 06:21-What makes COVID-19 different than the Swine Flu 08:43-How do we get accurate data on COVID-19?
  • 09:47-The Diamond Princess Cruise Quarantine
  • 15:12-Should everyone be tested?
  • 16:47-Italy & COVID-19
  • 23:06-Is self-isolation the best cure?
  • 27:06-Medical supplies shortage in New York
  • 29:48-But wait, what is a coronavirus?
  • 34:00-What is this pandemic’s outcome? 36:26-Identifying COVID-19 cases
  • 38:59-Why is COVID-19 putting a stress on the medical system?
  • 41:22-The “New Normal” in the face of COVID-19
  • 43:36-Is the cure worse than the disease?
  • 46:55-Are we over-preparing for the affects of COVID-19?
  • 47:55-The role of politics in the United States’ COVID-19 response
  • 49:23-Are the current isolation orders creating a bigger problem?
  • 52:20-High risk populations
  • 53:39-Biases in our COVID-19 response
  • 56:11-The World Health Organization’s role
  • 57:40-What can we learn from this pandemic?
  • 1:01:33-How long will the COVID-19 lockdown last?
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Videos

How to deal with COVID-19: Use your head because stupidty goes viral – Medical Director of the University Medical Center Essen

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News

Confirmed Coronavirus Cases Is an ‘Almost Meaningless’ Metric – Bloomberg / Yahoo Finance

“The numbers are almost meaningless,” says Steve Goodman, a professor of epidemiology at Stanford University. There’s a huge reservoir of people who have mild cases, and would not likely seek testing, he says. The rate of increase in positive results reflect a mixed-up combination of increased testing rates and spread of the virus.

https://finance.yahoo.com/news/confirmed-coronavirus-cases-almost-meaningless-123550415.html

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News

Covid19 no more dangerous than influenza says German immunologist and toxicologist, Professor Stefan Hockertz

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Videos

Corona virus COVID-19- hype and hysteria? – Prof. Dr. med. Sucharit Bhakdi

The original video has been censored by YouTube. A backup video can be found by scrolling down or visiting our archived video.

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News

Covid 19—many questions, no clear answers – Tom Jefferson – BMJ