Categories
Publications

Why no-one can ever recover from COVID-19 in England – a statistical anomaly – CEBM

Here, it seems that PHE regularly looks for people on the NHS database who have ever tested positive, and simply checks to see if they are still alive or not. PHE does not appear to consider how long ago the COVID test result was, nor whether the person has been successfully treated in hospital and discharged to the community. Anyone who has tested COVID positive but subsequently died at a later date of any cause will be included on the PHE COVID death figures.

By this PHE definition, no one with COVID in England is allowed to ever recover from their illness. A patient who has tested positive, but successfully treated and discharged from hospital, will still be counted as a COVID death even if they had a heart attack or were run over by a bus three months later.

https://www.cebm.net/covid-19/why-no-one-can-ever-recover-from-covid-19-in-england-a-statistical-anomaly/

Categories
Publications

Coronavirus Disease 2019 (COVID-19) Testing – CDC

A positive test result shows you may have antibodies from an infection with the virus that causes COVID-19. However, there is a chance a positive result means that you have antibodies from an infection with a virus from the same family of viruses (called coronaviruses), such as the one that causes the common cold.

Regardless of whether you test positive or negative, the results do not confirm whether or not you are able to spread the virus that causes COVID-19. 

https://www.cdc.gov/coronavirus/2019-ncov/testing/serology-overview.html

Categories
Opinion

Calm Down! Record Testing Is Why There Are Record “Cases” – William Briggs

Deaths decreasing as cases surge because of testing.

Testing is going nuts. Testing is out of control. Testing is rampant. Testing is at insane levels and only growing.

The number of daily COVID tests in the US
Official weekly dead according to the CDC as of 2 July for week ending 27 June

Notice anything? You might not have reached the apex of probability like I, the Statistician to the Stars! have, but surely you can see the most salient point. DEATHS ARE DECREASING, EVEN AS NEW “CASES” “SURGE” “SPIKE” “SOAR” “SET RECORDS”.

This is why we must continue to look to all-cause deaths are the best indicator. It’s just too easy to cheat, fudge, shade, tweak, adjust, or whatever word you like, with COVID deaths.

Categories
News

Coronavirus: Majority testing positive have no symptoms – BBC News

Only 22% of people testing positive for coronavirus reported having symptoms on the day of their test, according to the Office for National Statistics.

Note: the article deduces that this shows the importance of asymptomatic transmission. However, cases of asymptomatic transmission has been found to be very rare.

https://www.bbc.co.uk/news/health-53320155

Categories
Opinion

Coronavirus: Why everyone was wrong – Dr. Beda Stadler

Professor Dr. Beda M Stadler is the former director of the Institute for Immunology at the University of Bern, a biologist and professor emeritus.

Novelty:

Sars-Cov-2 isn’t all that new, but merely a seasonal cold virus that mutated and disappears in summer, as all cold viri do — which is what we’re observing globally right now. Flu viri mutate significantly more, by the way, and nobody would ever claim that a new flu virus strain was completely novel.

Immunity:

In mid-April work was published by the group of Andreas Thiel at the Charité Berlin. A paper with 30 authors, amongst them the virologist Christian Drosten. It showed that in 34 % of people in Berlin who had never been in contact with the Sars-CoV-2 virus showed nonetheless T-cell immunity against it (T-cell immunity is a different kind of immune reaction, see below). This means that our T-cells, i.e. white blood cells, detect common structures appearing on Sars-CoV-2 and regular cold viri and therefore combat both of them.

…almost no children under ten years old got sick, everyone should have made the argument that children clearly have to be immune. For every other disease that doesn’t afflict a certain group of people, we would come to the conclusion that that group is immune. When people are sadly dying in a retirement home, but in the same place other pensioners with the same risk factors are left entirely unharmed, we should also conclude that they were presumably immune.

Modelling:

Epidemiologist also fell for the myth that there was no immunity in the population. They also didn’t want to believe that coronaviri were seasonal cold viri that would disappear in summer. Otherwise their curve models would have looked differently. When the initial worst case scenarios didn’t come true anywhere, some now still cling to models predicting a second wave.

Asymptomatic transmission:

The term “silent carriers” was conjured out of a hat and it was claimed that one could be sick without having symptoms.

The next joke that some virologists shared was the claim that those who were sick without symptoms could still spread the virus to other people…But for doctors and virologists to twist this into a story of “healthy” sick people, which stokes panic and was often given as a reason for stricter lockdown measures, just shows how bad the joke really is. At least the WHO didn’t accept the claim of asymptomatic infections and even challenges this claim on its website.

Testing:

So if we do a PCR corona test on an immune person, it is not a virus that is detected, but a small shattered part of the viral genome. The test comes back positive for as long as there are tiny shattered parts of the virus left. Correct: Even if the infectious viri are long dead, a corona test can come back positive, because the PCR method multiplies even a tiny fraction of the viral genetic material enough [to be detected]…The crux was that the virus debris registered with the overly sensitive test and therefore came back as “positive”. It is likely that a large number of the daily reported infection numbers are purely due to viral debris.

Kawasaki Syndrome:

If an infected person does not have enough antibodies, i.e. a weak immune response, the virus slowly spreads out across the entire body. Now that there are not enough antibodies, there is only the second, supporting leg of our immune response left: The T-cells beginn to attack the virus-infested cells all over the body. This can lead to an exaggerated immune response, basically to a massive slaughter; this is called a Cytokine Storm. Very rarely this can also happen in small children, in that case called Kawasaki Syndrome. This very rare occurrence in children was also used in our country to stoke panic. It’s interesting, however, that this syndrome is very easily cured. The [affected] children get antibodies from healthy blood donors, i.e. people who went through coronavirus colds.

Second Wave:

The virus is gone for now. It will probably come back in winter, but it won’t be a second wave, but just a cold.

Face masks:

Those young and healthy people who currently walk around with a mask on their faces would be better off wearing a helmet instead, because the risk of something falling on their head is greater than that of getting a serious case of Covid-19.

Lethality:

People below 65 years old make up only 0.6 to 2.6 % of all fatal Covid cases. To get on top of the pandemic, we need a strategy merely concentrating on the protection of at-risk people over 65.

https://medium.com/@vernunftundrichtigkeit/coronavirus-why-everyone-was-wrong-fce6db5ba809

Categories
Opinion

Opting out of NHS Test and Trace

According to government guidelines, the public will be asked to provide their names and phone numbers to the venues and businesses they visit from Saturday 4th July 2020.

Be aware that this is done on a voluntary basis. You are under no legal obligation to leave your details or provide correct information. The business should not refuse to serve you if you do not wish to provide your information.

The relevant section of the government guidelines is shown below.

Source: Department of Health and Social Care Guidance, 2 July 2020

The complete text for the guidelines can be found in a document that can be downloaded from the GOV.UK website: Maintaining records of staff, customers and visitors to support NHS Test and Trace

Information collected

If you choose to provide information as a customer, government guidelines state that only the following details should be collected:

  • The name of the customer or visitor. If there is more than one person, then you can record the name of the ‘lead member’ of the group and the number of people in the group.
  • A contact phone number for each customer or visitor, or for the lead member of a group of people.
  • Date of visit, arrival time and, where possible, departure time.
  • If a customer will interact with only one member of staff (e.g. a hairdresser), the name of the assigned staff member should be recorded alongside the name of the customer.

Booking and reservation information

The information you provide when making a booking or reservation may be shared with NHS Test and Trace. If you do not wish your details to be used for this purpose, you should inform the business that you wish to opt out of NHS Test and Trace.

General Data Protection Regulation (GDPR)

NHS Test and Trace is subject to GDPR. This means that the business is legally obliged to handle your details in accordance with the regulation. However, be aware that under GDPR, the business is not required to:

  • Individually inform customers about how their information will be used.
  • Seek consent to collect data from individual customers.

If in doubt, make sure you explicitly inform management that you are opting out and any details you provide should not be used for NHS Test and Trace.

Why you should opt out of NHS Test and Trace

While we cannot give you advice about leaving your contact details, we believe that opting out of NHS Test and Trace is the right thing to do. This is because:

  1. The tests for COVID-19 are known to be inaccurate, resulting in high false positives and false negatives.
  2. These inaccurate results may be used to justify local lock-downs which will have a severely negative impact on your area.
  3. You will be traced and told self-isolate if anyone you have been in contact with during your visit tests positive, even if it is a false positive.
  4. The tracing system rollout was rushed and did not complete mandatory privacy checks. NHS Test and Trace is facing a legal challenge because it does not have strong enough safeguards.
  5. Your data will be held for 20 years. There is no way to know how the information collected about you will be used by a future political administration.
Categories
Publications

Impact of false positives and negatives, 3 June 2020 – Government Office for Science

The UK operational false positive rate is unknown. There are no published studies on the operational false positive rate of any national COVID-19 testing programme.

An attempt has been made to estimate the likely false-positive rate of national COVID-19 testing programmes by examining data from published external quality assessments (EQAs) for RT-PCR assays for other RNA viruses carried out between 2004-2019 [7]. Results of 43 EQAs were examined, giving a median false positive rate of 2.3% (interquartile range 0.8-4.0%).

Alistair Haimes interpreted these results in this way:

2.3% false positive rate with 0.04% virus prevalence rate (ONS) means that if you test positive you have only a 4/234= 1.7% chance of being infected. We’re flying blind.

if the false positive rate is that high, surely they just know that it is ‘about nothing’; 0.04% must be false precision?

@AlistairHaimes. 3 July 2020

https://www.gov.uk/government/publications/gos-impact-of-false-positives-and-negatives-3-june-2020

Categories
Publications

Officially-reported COVID-19 deaths in Ireland likely overestimates – HIQA

HIQA found that the officially-reported COVID-19 deaths likely overestimates the true burden of excess deaths caused by the virus. This could be due to the inclusion within official figures of people who were infected with SARS-CoV-2 (coronavirus) at the time of death whose cause of death may have been predominantly due to other factors.

https://www.hiqa.ie/hiqa-news-updates/covid-19-causes-13-increase-deaths-ireland-between-march-and-june-2020-hiqa

Categories
Publications

80.9% of care home residents who tested positive were asymptomatic – Department of Health & Social Care

  • 2.4% of all tests were positive (9,674 out of 397,197)
  • 3.9% of residents tested positive (6,747 out of 172,066)
  • 3.3% of asymptomatic residents tested positive (5,455 out of 163,945)
  • 80.9% of residents who tested positive were asymptomatic (5,455 out of 6,747)
  • 1.2% of asymptomatic staff tested positive (2,567 out of 210,620)

https://www.gov.uk/government/publications/vivaldi-1-coronavirus-covid-19-care-homes-study-report/vivaldi-1-covid-19-care-homes-study-report

Categories
Publications

Sentinel surveillance of SARS-CoV-2 in wastewater anticipates the occurrence of COVID-19 cases – medRxiv

SARS-CoV-2 was detected in Barcelona sewage long before the declaration of the first COVID-19 case, indicating that the infection was present in the population before the first imported case was reported. Sentinel surveillance of SARS-CoV-2 in wastewater would enable adoption of immediate measures in the event of future COVID-19 waves.

https://www.medrxiv.org/content/10.1101/2020.06.13.20129627v1

Categories
News

Masks Don’t Work: A Review of Science Relevant to COVID-19 Social Policy – Denis Rancourt (PhD) The River Cities’ Reader

No RCT study with verified outcome shows a benefit for HCW or community members in households to wearing a mask or respirator. There is no such study. There are no exceptions.

Likewise, no study exists that shows a benefit from a broad policy to wear masks in public.

Furthermore, if there were any benefit to wearing a mask, because of the blocking power against droplets and aerosol particles, then there should be more benefit from wearing a respirator (N95) compared to a surgical mask, yet several large meta-analyses, and all the RCT, prove that there is no such relative benefit.

Regarding the aerosol mechanism of infectious disease transmission:

Mask stoppage efficiency and host inhalation are only half of the equation, however, because the minimal infective dose (MID) must also be considered. For example, if a large number of pathogen-laden particles must be delivered to the lung within a certain time for the illness to take hold, then partial blocking by any mask or cloth can be enough to make a significant difference.

On the other hand, if the MID is amply surpassed by the virions carried in a single aerosol particle able to evade mask-capture, then the mask is of no practical utility, which is the case.

[I]f anything gets through (and it always does, irrespective of the mask), then you are going to be infected. Masks cannot possibly work. It is not surprising, therefore, that no bias-free study has ever found a benefit from wearing a mask or respirator in this application.

Regarding minimal infective dose:

  • Most respiratory viruses are as infective in humans as in tissue culture having optimal laboratory susceptibility
  • It is believed that a single virion can be enough to induce illness in the host
  • The 50-percent probability MID (“TCID50”) has variably been found to be in the range 100−1000 virions
  • There are typically 10 to 3rd power − 10 to 7th power virions per aerolized influenza droplet with diameter 1 μm − 10 μm
  • The 50-percent probability MID easily fits into a single (one) aerolized droplet
  • For further background:
  • A classic description of dose-response assessment is provided by Haas (1993).
  • Zwart et al. (2009) provided the first laboratory proof, in a virus-insect system, that the action of a single virion can be sufficient to cause disease.
  • Baccam et al. (2006) calculated from empirical data that, with influenza A in humans,“we estimate that after a delay of ~6 h, infected cells begin producing influenza virus and continue to do so for ~5 h. The average lifetime of infected cells is ~11 h, and the half-life of free infectious virus is ~3 h. We calculated the [in-body] basic reproductive number, R0, which indicated that a single infected cell could produce ~22 new productive infections.”
  • Brooke et al. (2013) showed that, contrary to prior modeling assumptions, although not all influenza-A-infected cells in the human body produce infectious progeny (virions), nonetheless, 90 percent of infected cell are significantly impacted, rather than simply surviving unharmed.

Regarding tests for a wide-scale mask-wearing policy:

  • Any benefit from mask-wearing would have to be a small effect, since undetected in controlled experiments, which would be swamped by the larger effects, notably the large effect from changing atmospheric humidity.
  • Mask compliance and mask adjustment habits would be unknown.
  • Mask-wearing is associated (correlated) with several other health behaviors; see Wada (2012).
  • The results would not be transferable, because of differing cultural habits.
  • Compliance is achieved by fear, and individuals can habituate to fear-based propaganda, and can have disparate basic responses.
  • Monitoring and compliance measurement are near-impossible, and subject to large errors.
  • Self-reporting (such as in surveys) is notoriously biased, because individuals have the self-interested belief that their efforts are useful.
  • Progression of the epidemic is not verified with reliable tests on large population samples, and generally relies on non-representative hospital visits or admissions.
  • Several different pathogens (viruses and strains of viruses) causing respiratory illness generally act together, in the same population and/or in individuals, and are not resolved, while having different epidemiological characteristics.

Unanswered questions about mask-wearing:

  • Do used and loaded masks become sources of enhanced transmission, for the wearer and others?
  • Do masks become collectors and retainers of pathogens that the mask wearer would otherwise avoid when breathing without a mask?
  • Are large droplets captured by a mask atomized or aerolized into breathable components? Can virions escape an evaporating droplet stuck to a mask fiber?
  • What are the dangers of bacterial growth on a used and loaded mask?
  • How do pathogen-laden droplets interact with environmental dust and aerosols captured on the mask?
  • What are long-term health effects on HCW, such as headaches, arising from impeded breathing?
  • Are there negative social consequences to a masked society?
  • Are there negative psychological consequences to wearing a mask, as a fear-based behavioral modification?
  • What are the environmental consequences of mask manufacturing and disposal?
  • Do the masks shed fibers or substances that are harmful when inhaled?

https://www.rcreader.com/commentary/masks-dont-work-covid-a-review-of-science-relevant-to-covide-19-social-policy

Categories
Publications

Interpreting a covid-19 test result – BMJ

No test gives a 100% accurate result; tests need to be evaluated to determine their sensitivity and specificity, ideally by comparison with a “gold standard.” The lack of such a clear-cut “gold-standard” for covid-19 testing makes evaluation of test accuracy challenging.

A systematic review of the accuracy of covid-19 tests reported false negative rates of between 2% and 29% (equating to sensitivity of 71-98%), based on negative RT-PCR tests which were positive on repeat testing. The use of repeat RT-PCR testing as gold standard is likely to underestimate the true rate of false negatives, as not all patients in the included studies received repeat testing and those with clinically diagnosed covid-19 were not considered as actually having covid-19.

Further evidence and independent validation of covid-19 tests are needed. As current studies show marked variation and are likely to overestimate sensitivity, we will use the lower end of current estimates from systematic reviews, with the approximate numbers of 70% for sensitivity and 95% for specificity for illustrative purposes.

https://www.bmj.com/content/369/bmj.m1808

Categories
Publications

Variation in False-Negative Rate of Reverse Transcriptase Polymerase Chain Reaction–Based SARS-CoV-2 Tests by Time Since Exposure – Annals of Internal Medicine

However, new research from Johns Hopkins University (MD, USA) has found that the chance of these tests giving a false negative – stating no infection when the individual actually is infected – is greater than 1 in 5, at times being far higher. The study, which analyzed seven previously published studies that evaluated RT-PCR performance, calls into question the accuracy of the predictive value of such tests.

Biotechniques, 29 May 2020

https://www.acpjournals.org/doi/10.7326/M20-1495

Categories
Publications

Sir David Norgrove response to Matt Hancock regarding the Government’s COVID-19 testing data – UK Statistics Authority

The way the data are analysed and presented currently gives them limited value for the first purpose [of understanding the epidemic]. The aim seems to be to show the largest possible number of tests, even at the expense of understanding. It is also hard to believe the statistics work to support the testing programme itself. The statistics and analysis serve neither purpose well.

https://www.statisticsauthority.gov.uk/correspondence/sir-david-norgrove-response-to-matt-hancock-regarding-the-governments-covid-19-testing-data/
Categories
Visitor Contributions

A Comprehensive Analysis of the Covid Crisis – Joyti Valérian Goel

In the interest of public debate, we allow visitors to share opinions, experiences and research that may be of value to others. This is a visitor contribution from our Discussions page.

The views expressed are those of the individual posters themselves. Please read our Comments and contributions disclaimer.

Authors

Joyti Valérian Goel

Bio: I am of Service to Others, I want to contribute towards the paradigm shift, help people understand what is at stake, to help them make wise decisions, find their paths and progress as human beings.


This document synthesizes practically all aspects of the crisis and that it is to be fully understood once you read it from A to Z because everything is interconnected.

Everybody is entitled to their perspective and has the right to disagree with anything stated in this document. However, I urge you to read the document from A to Z with an open mind before making any decision. I have laid out useful insights and raised pertinent questions in order to appeal to your intellect and instigate enough curiosity so that you can also start researching yourself what is truly going on.

Some of the pertinent question:
• Does the virus exist and if it does, where does it come from?
• Why do so many positive patients suffer from minor or no symptoms?
• What test do they use?
• How do they report a death or a case?
• Why was Italy hit so badly?
• Will things ever go back to normal?
• Are there any links between 5G and the virus?
• What is this pandemic accomplishing?
• Who is benefiting from it?
• What are they hiding from us?
• What can we do?

Download the full paper: https://joytigoel.com/A-Comprehensive-Analysis-of-the-Covid-19-Crisis.pdf

Categories
Opinion

Why has coronavirus fled London? – The Spectator

[I]f you believe herd immunity is only reached at 60 per cent, you should be terrified at any loosening of lockdown. If you don’t, then you must reconcile antibody testing that says 80 per cent are still susceptible with the difficulty the virus seems to encounter in marching very far past 20 percent of the population.

That is the reconciliation my hypothesis achieves. I propose that there may exist forms of human resistance to this virus that don’t show up in Covid-19 antibody tests.

[I]n focusing on that Covid antibody test alone as indicating a pass-or-fail immunity, we could be overlooking important ways in which humans may be endowed with, or acquire, other kinds of resistance. 

https://www.spectator.co.uk/article/why-has-coronavirus-fled-london-

Categories
Opinion

Coronavirus doesn’t care about politics – UnHerd

So as you read, in coming weeks, furious news stories about technical incompetence, citizen non-compliance, threats of stricter enforcement and blame in all directions, as if everything was hanging on the latest government policy, remember the humility of scientists instead of the solipsism of the political class. Yes, the Government action plan will most likely be ineffective, but politicians were never in charge of this anyway. It’s bigger than they are — the best they could ever hope to do is tinker around the edges. Coronavirus is nobody’s ‘fault’.

https://unherd.com/2020/05/coronavirus-doesnt-care-about-politics/
Categories
Opinion

I’ve signed death certificates during Covid-19. Here’s why you can’t trust any of the statistics on the number of victims – Dr. Malcolm Kendrick, RT

As an NHS doctor, I’ve seen people die and be listed as a victim of coronavirus without ever being tested for it. But unless we have accurate data, we won’t know which has killed more: the disease or the lockdown?

It matters greatly for two main reasons. First, if we vastly overestimate deaths from Covid-19, we will greatly underestimate the harm caused by the lockdown. This issue was looked at in a recent article published in the BMJ, The British Medical Journal.  It stated: “Only a third of the excess deaths seen in the community in England and Wales can be explained by Covid-19.

If Covid-19 killed 30,000, and lockdown killed the other 30,000, then the lockdown was a complete and utter waste of time. and should never happen again. The great fear is that this would be a message this government does not want to hear – so they will do everything possible not to hear it.

https://www.rt.com/op-ed/490006-death-certificates-covid-19-do-not-trust/

Categories
News

Government coronavirus contact tracing site CRASHES within minutes of launching as staff reveal first shift has been a ‘complete shambles’ – Daily Mail

The government’s coronavirus contact tracing site crashed on launch this morning amid complaints it has been a ‘complete shambles’.

Doctors and other staff reported major teething troubles as the much-trumpeted scheme finally got up and running, with some saying they had not even received passwords to start work.

https://www.dailymail.co.uk/news/article-8364799/Matt-Hancock-LAUGHS-suggestion-rushed-contact-tracing-scheme.html

Categories
News

Health regulator tells laboratories to STOP analysing all samples from Covid-19 home antibody tests – Daily Mail

US CDC that antibody tests for Covid-19 may be wrong up to half of the time.

The CDC now warns antibody testing is not accurate enough for it to be used for any policy-making decisions, as even with high test specificity, ‘less than half of those testing positive will truly have antibodies’.

There is currently a high level of inaccuracy in the testing, however, caused by how uncommon the virus is within the population.

https://www.dailymail.co.uk/news/article-8358729/Health-regulator-tells-laboratories-STOP-analysing-samples-Covid-19-home-antibody-tests.html