Variation in False-Negative Rate of Reverse Transcriptase Polymerase Chain Reaction–Based SARS-CoV-2 Tests by Time Since Exposure – Annals of Internal Medicine

However, new research from Johns Hopkins University (MD, USA) has found that the chance of these tests giving a false negative – stating no infection when the individual actually is infected – is greater than 1 in 5, at times being far higher. The study, which analyzed seven previously published studies that evaluated RT-PCR performance, calls into question the accuracy of the predictive value of such tests.

Biotechniques, 29 May 2020