Nature published a comprehensive study this week on cardiovascular risk including a total of over 11 million patients that has made a few headlines. The aim was to identify the cause of increased cardiac pathology. It should have been a very simple study comparing four groups:
Not infected and never vaccinated
Not infected and vaccinated
Infected but not vaccinated
Infected and vaccinated
It is hard to believe the authors did not look at these groups, but whatever was found when comparing them remains a mystery.
Instead, the following groups were compared:
Not infected and never vaccinated data from 2017
Not infected, including vaccinated and not vaccinated
Infected but not vaccinated
Infected with vaccinated people included but using modelled adjustments
When studies with huge datasets use modelling and fail to share data prior to their adjustments alarm bells should start ringing. Therefore, I took a deeper dive to see what else was questionable.
The cardiovascular complications of acute coronavirus disease 2019 (COVID-19) are well described, but the post-acute cardiovascular manifestations of COVID-19 have not yet been comprehensively characterized. Here we used national healthcare databases from the US Department of Veterans Affairs to build a cohort of 153,760 individuals with COVID-19, as well as two sets of control cohorts with 5,637,647 (contemporary controls) and 5,859,411 (historical controls) individuals, to estimate risks and 1-year burdens of a set of pre-specified incident cardiovascular outcomes. We show that, beyond the first 30 d after infection, individuals with COVID-19 are at increased risk of incident cardiovascular disease spanning several categories, including cerebrovascular disorders, dysrhythmias, ischemic and non-ischemic heart disease, pericarditis, myocarditis, heart failure and thromboembolic disease. These risks and burdens were evident even among individuals who were not hospitalized during the acute phase of the infection and increased in a graded fashion according to the care setting during the acute phase (non-hospitalized, hospitalized and admitted to intensive care). Our results provide evidence that the risk and 1-year burden of cardiovascular disease in survivors of acute COVID-19 are substantial. Care pathways of those surviving the acute episode of COVID-19 should include attention to cardiovascular health and disease.
OVER a quarter of a million Brits could face a new heart-related illness due to the stress of the Covid pandemic, experts have warned.
Poor diet, lack of physical activity and stress and mental health issues can all have an impact on our heart.
Now a leading NHS mental health services provider and senior vascular surgeon, Mark Rayner, says Brits are facing a ‘trauma timebomb’ that will see them at risk of heart disease and fatal heart attacks due the effects of PPSD (Post Pandemic Stress Disorder).