Assessment of Maternal and Neonatal SARS-CoV-2 Viral Load, Transplacental Antibody Transfer, and Placental Pathology in Pregnancies During the COVID-19 Pandemic – JAMA

Post author By EvidenceNotFear
Post date 22 December 2020

Conclusions and Relevance In this cohort study, there was no evidence of placental infection or definitive vertical transmission of SARS-CoV-2. Transplacental transfer of anti-SARS-CoV-2 antibodies was inefficient. Lack of viremia and reduced coexpression and colocalization of placental angiotensin-converting enzyme 2 and transmembrane serine protease 2 may serve as protective mechanisms against vertical transmission.

https://web.archive.org/web/20201222162005/https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2774428

Tags Antibodies, COVID-19, Infection, JAMA, Neonatal, Pregnant, SARS-CoV-2, Transmission, Viral Load

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