Summary of pharmacokinetic study – Pharmaceuticals and Medical Devices Agency Japan

Liver samples were collected over time and the concentrations of ALC-0315 and ALC-0159 in each sample were measured. The conclusion As a result, ALC-0315 and ALC-0159 were shown to be rapidly distributed from the blood to the liver. Also, About 1% and about 50% of the doses of ALC-0315 and ALC-0159 are excreted in feces as unchanged drug, respectively.